Is E78.6 a billable ICD-10-CM code?

Yes. E78.6 is a billable, specific ICD-10-CM code and is valid for submission on a claim.

Where does E78.6 sit in the tabular list?

Endocrine, nutritional and metabolic diseases (E00-E89), in the block Metabolic disorders (E70-E88).

What cannot be coded together with E78.6?

E78.6 carries Excludes1 notes, which means the conditions they list can never be coded together with it on the same encounter. Some are written on the categories above E78.6 (E78) and apply to it just the same.

E78.6

E78.6 — Lipoprotein deficiency

Billable / specific codeICD-10-CM

E78.6 is a billable, specific ICD-10-CM code for lipoprotein deficiency. It is valid for submission on a claim.

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

Abetalipoproteinemia
Depressed HDL cholesterol
High-density lipoprotein deficiency
Hypoalphalipoproteinemia
Hypobetalipoproteinemia (familial)
Lecithin cholesterol acyltransferase deficiency
Tangier disease

Excludes1 inherited from the categories above E78.6

These are not written on E78.6, but they bind it: a note on a category applies to every code beneath it. Billing E78.6 with anything listed here is a denial.

Written on E78 — Disorders of lipoprotein metabolism and other lipidemias

sphingolipidosis (E75.0-E75.3)

Risk adjustment

E78.6 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Medicare coverage

E78.6 is named in 6 Medicare coverage policies — 6 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

A54969Billing and Coding: Nerve Conduction Studies and Electromyography
A56619Billing and Coding: Nerve Conduction Studies and Electromyography
A57307Billing and Coding: Nerve Conduction Studies and Electromyography
A57326Billing and Coding: Electrocardiograms

How E78.6 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to E78.6.

Abetalipoproteinemia
Acanthocytosis
Analphalipoproteinemia
Bassen-Kornzweig disease or syndrome
Hypoalphalipoproteinemia
Hypobetalipoproteinemia(familial)
Hypolipoproteinemia(alpha) (beta)
Tangier disease
Deficiency, deficient›lecithin cholesterol acyltransferase
Deficiency, deficient›lipoprotein(familial) (high density)
Depressed›HDL cholesterol
Disease, diseased›Tangier

Code history

E78.6 has not changed since FY2024 — no addition, revision or deletion across the three most recent ICD-10-CM releases.

Related codes at this level

Codes that share E78. If E78.6 is not quite right, the correct code is usually one of these.

Questions about E78.6

Is E78.6 a billable ICD-10-CM code?: Yes. E78.6 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does E78.6 sit in the tabular list?: Endocrine, nutritional and metabolic diseases (E00-E89), in the block Metabolic disorders (E70-E88).
What cannot be coded together with E78.6?: E78.6 carries Excludes1 notes, which means the conditions they list can never be coded together with it on the same encounter. Some are written on the categories above E78.6 (E78) and apply to it just the same.