MCMedicalCodingSoftware
E78.49

E78.49: Other hyperlipidemia

Billable / specific codeICD-10-CM

E78.49 is a billable, specific ICD-10-CM code for other hyperlipidemia. It is valid for submission on a claim.

Check E78.49 with the rest of the claim: free scrubber

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Familial combined hyperlipidemia

Excludes1 inherited from the categories above E78.49

A category’s note binds every code beneath it.

Written on E78: Disorders of lipoprotein metabolism and other lipidemias

Other codes that can never be billed with E78.49

Their own Excludes1 notes name this code, so the conflict is not listed above.

  • E78.2Mixed hyperlipidemia

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

E78.49 is named in 12 Medicare coverage policies: 12 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A56416Billing and Coding: Assays for Vitamins and Metabolic Function
  • A56422Billing and Coding: Bariatric Surgical Management of Morbid Obesity
  • A56675Billing and Coding: Homocysteine Level, Serum
  • A56943Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment

Alphabetic index entries that lead here

  • Hyperlipemia, hyperlipidemia›specified NEC
  • Hyperlipemia, hyperlipidemia›combined›familial

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under E78.4

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.