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D76.3

D76.3: Other histiocytosis syndromes

Billable / specific codeICD-10-CM

D76.3 is a billable, specific ICD-10-CM code for other histiocytosis syndromes. It is valid for submission on a claim.

Check D76.3 with the rest of the claim: free scrubber

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Reticulohistiocytoma (giant-cell)
  • Sinus histiocytosis with massive lymphadenopathy
  • Xanthogranuloma

Excludes1 inherited from the categories above D76.3

A category’s note binds every code beneath it.

Written on D76: Other specified diseases with participation of lymphoreticular and reticulohistiocytic tissue

  • (Abt-) Letterer-Siwe disease (C96.0)
  • eosinophilic granuloma (C96.6)
  • Hand-Schüller-Christian disease (C96.5)
  • histiocytic medullary reticulosis (C96.9)
  • histiocytic sarcoma (C96.A)
  • histiocytosis X, multifocal (C96.5)
  • histiocytosis X, unifocal (C96.6)
  • Langerhans-cell histiocytosis, multifocal (C96.5)
  • Langerhans-cell histiocytosis NOS (C96.6)
  • Langerhans-cell histiocytosis, unifocal (C96.6)
  • leukemic reticuloendotheliosis (C91.4-)
  • lipomelanotic reticulosis (I89.8)
  • malignant histiocytosis (C96.A)
  • malignant reticulosis (C86.0)
  • nonlipid reticuloendotheliosis (C96.0)

Risk adjustment

D76.3 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:

  • HCC 115 Specified Immunodeficiencies and White Blood Cell Disorders0.565 RAF

Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score. Look up the whole chart to see which of its HCCs the hierarchy would zero.

Medicare coverage

D76.3 is named in 9 Medicare coverage policies: 9 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A55717Billing and Coding: Lab: Flow Cytometry
  • A56464Billing and Coding: Flow Cytometry
  • A57689Billing and Coding: Lab: Flow Cytometry
  • A59101Billing and Coding: Off-label Use of Rituximab and Rituximab Biosimilars

Alphabetic index entries that lead here

  • Histiocytosis
  • Reticulohistiocytoma(giant-cell)
  • Xanthogranuloma
  • Granuloma›reticulohistiocytic
  • Histiocytosis›lipid, lipoid
  • Histiocytosis›non-Langerhans cell
  • Histiocytosis›polyostotic sclerosing
  • Histiocytosis›sinus, with massive lymphadenopathy
  • Histiocytosis›syndrome NEC
  • Lipoid›histiocytosis
  • Syndrome›histiocytic
  • Syndrome›histiocytosis NEC

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under D76

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.