D76.3 — Other histiocytosis syndromes
D76.3 is a billable, specific ICD-10-CM code for other histiocytosis syndromes. It is valid for submission on a claim.
Inclusion terms
Alternative wordings a physician may use in the chart for this same code.
- Reticulohistiocytoma (giant-cell)
- Sinus histiocytosis with massive lymphadenopathy
- Xanthogranuloma
Excludes1 inherited from the categories above D76.3
These are not written on D76.3, but they bind it: a note on a category applies to every code beneath it. Billing D76.3 with anything listed here is a denial.
Written on D76 — Other specified diseases with participation of lymphoreticular and reticulohistiocytic tissue
- (Abt-) Letterer-Siwe disease (C96.0)
- eosinophilic granuloma (C96.6)
- Hand-Schüller-Christian disease (C96.5)
- histiocytic medullary reticulosis (C96.9)
- histiocytic sarcoma (C96.A)
- histiocytosis X, multifocal (C96.5)
- histiocytosis X, unifocal (C96.6)
- Langerhans-cell histiocytosis, multifocal (C96.5)
- Langerhans-cell histiocytosis NOS (C96.6)
- Langerhans-cell histiocytosis, unifocal (C96.6)
- leukemic reticuloendotheliosis (C91.4-)
- lipomelanotic reticulosis (I89.8)
- malignant histiocytosis (C96.A)
- malignant reticulosis (C86.0)
- nonlipid reticuloendotheliosis (C96.0)
Risk adjustment
D76.3 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:
- HCC 115 Specified Immunodeficiencies and White Blood Cell Disorders0.565 RAF
Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score.
Medicare coverage
D76.3 is named in 17 Medicare coverage policies — 17 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.
- A55717Billing and Coding: Lab: Flow Cytometry
- A56464Billing and Coding: Flow Cytometry
- A57689Billing and Coding: Lab: Flow Cytometry
- A59101Billing and Coding: Off-label Use of Rituximab and Rituximab Biosimilars
How D76.3 is indexed
Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to D76.3.
- Histiocytosis
- Reticulohistiocytoma(giant-cell)
- Xanthogranuloma
- Granuloma›reticulohistiocytic
- Histiocytosis›lipid, lipoid
- Histiocytosis›non-Langerhans cell
- Histiocytosis›polyostotic sclerosing
- Histiocytosis›sinus, with massive lymphadenopathy
- Histiocytosis›syndrome NEC
- Lipoid›histiocytosis
- Syndrome›histiocytic
- Syndrome›histiocytosis NEC
Code history
D76.3 has not changed since FY2024 — no addition, revision or deletion across the three most recent ICD-10-CM releases.
Related codes at this level
Codes that share D76. If D76.3 is not quite right, the correct code is usually one of these.
Questions about D76.3
- Is D76.3 a billable ICD-10-CM code?
- Yes. D76.3 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
- Where does D76.3 sit in the tabular list?
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89), in the block Other disorders of blood and blood-forming organs (D70-D77).
- What cannot be coded together with D76.3?
- D76.3 carries Excludes1 notes, which means the conditions they list can never be coded together with it on the same encounter. Some are written on the categories above D76.3 (D76) and apply to it just the same.