Is D76.2 a billable ICD-10-CM code?

Yes. D76.2 is a billable, specific ICD-10-CM code and is valid for submission on a claim.

Where does D76.2 sit in the tabular list?

Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89), in the block Other disorders of blood and blood-forming organs (D70-D77).

What cannot be coded together with D76.2?

D76.2 carries Excludes1 notes, which means the conditions they list can never be coded together with it on the same encounter. Some are written on the categories above D76.2 (D76) and apply to it just the same.

D76.2

D76.2 — Hemophagocytic syndrome, infection-associated

Billable / specific codeICD-10-CM

D76.2 is a billable, specific ICD-10-CM code for hemophagocytic syndrome, infection-associated. It is valid for submission on a claim.

Use additional code

Add a secondary code to capture the detail described below.

code to identify infectious agent or disease.

Excludes1 inherited from the categories above D76.2

These are not written on D76.2, but they bind it: a note on a category applies to every code beneath it. Billing D76.2 with anything listed here is a denial.

Written on D76 — Other specified diseases with participation of lymphoreticular and reticulohistiocytic tissue

(Abt-) Letterer-Siwe disease (C96.0)
eosinophilic granuloma (C96.6)
Hand-Schüller-Christian disease (C96.5)
histiocytic medullary reticulosis (C96.9)
histiocytic sarcoma (C96.A)
histiocytosis X, multifocal (C96.5)
histiocytosis X, unifocal (C96.6)
Langerhans-cell histiocytosis, multifocal (C96.5)
Langerhans-cell histiocytosis NOS (C96.6)
Langerhans-cell histiocytosis, unifocal (C96.6)
leukemic reticuloendotheliosis (C91.4-)
lipomelanotic reticulosis (I89.8)
malignant histiocytosis (C96.A)
malignant reticulosis (C86.0)
nonlipid reticuloendotheliosis (C96.0)

Risk adjustment

D76.2 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Medicare coverage

D76.2 is named in 3 Medicare coverage policies — 3 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

A55717Billing and Coding: Lab: Flow Cytometry
A56464Billing and Coding: Flow Cytometry
A57689Billing and Coding: Lab: Flow Cytometry

How D76.2 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to D76.2.

Syndrome›hemophagocytic, infection-associated
Syndrome›macrophage activation›due to infection

Code history

D76.2 has not changed since FY2024 — no addition, revision or deletion across the three most recent ICD-10-CM releases.

Related codes at this level

Codes that share D76. If D76.2 is not quite right, the correct code is usually one of these.

Questions about D76.2

Is D76.2 a billable ICD-10-CM code?: Yes. D76.2 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does D76.2 sit in the tabular list?: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89), in the block Other disorders of blood and blood-forming organs (D70-D77).
What cannot be coded together with D76.2?: D76.2 carries Excludes1 notes, which means the conditions they list can never be coded together with it on the same encounter. Some are written on the categories above D76.2 (D76) and apply to it just the same.