MCMedicalCodingSoftware
D76.2

D76.2: Hemophagocytic syndrome, infection-associated

Billable / specific codeICD-10-CM

D76.2 is a billable, specific ICD-10-CM code for hemophagocytic syndrome, infection-associated. It is valid for submission on a claim.

Check D76.2 with the rest of the claim: free scrubber

Use additional code

Add a secondary code to capture the detail described below.

  • code to identify infectious agent or disease.

Excludes1 inherited from the categories above D76.2

A category’s note binds every code beneath it.

Written on D76: Other specified diseases with participation of lymphoreticular and reticulohistiocytic tissue

  • (Abt-) Letterer-Siwe disease (C96.0)
  • eosinophilic granuloma (C96.6)
  • Hand-Schüller-Christian disease (C96.5)
  • histiocytic medullary reticulosis (C96.9)
  • histiocytic sarcoma (C96.A)
  • histiocytosis X, multifocal (C96.5)
  • histiocytosis X, unifocal (C96.6)
  • Langerhans-cell histiocytosis, multifocal (C96.5)
  • Langerhans-cell histiocytosis NOS (C96.6)
  • Langerhans-cell histiocytosis, unifocal (C96.6)
  • leukemic reticuloendotheliosis (C91.4-)
  • lipomelanotic reticulosis (I89.8)
  • malignant histiocytosis (C96.A)
  • malignant reticulosis (C86.0)
  • nonlipid reticuloendotheliosis (C96.0)

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

D76.2 is named in 3 Medicare coverage policies: 3 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A55717Billing and Coding: Lab: Flow Cytometry
  • A56464Billing and Coding: Flow Cytometry
  • A57689Billing and Coding: Lab: Flow Cytometry

Alphabetic index entries that lead here

  • Syndrome›hemophagocytic, infection-associated
  • Syndrome›macrophage activation›due to infection

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under D76

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.