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D58.2

D58.2Other hemoglobinopathies

Billable / specific codeICD-10-CM

D58.2 is a billable, specific ICD-10-CM code for other hemoglobinopathies. It is valid for submission on a claim.

Excludes1 — never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • familial polycythemia (D75.0)
  • Hb-M disease (D74.0)
  • hemoglobin E-beta thalassemia (D56.5)
  • hereditary persistence of fetal hemoglobin [HPFH] (D56.4)
  • high-altitude polycythemia (D75.1)
  • methemoglobinemia (D74.-)
  • other hemoglobinopathies with thalassemia (D56.8)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Abnormal hemoglobin NOS
  • Congenital Heinz body anemia
  • Hb-C disease
  • Hb-D disease
  • Hb-E disease
  • Hemoglobinopathy NOS
  • Unstable hemoglobin hemolytic disease

Other codes that can never be billed with D58.2

These codes carry an Excludes1 note pointing at D58.2. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading D58.2 alone.

  • D56.5Hemoglobin E-beta thalassemia
  • D56.8Other thalassemias

Risk adjustment

D58.2 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Medicare coverage

D58.2 is named in 4 Medicare coverage policies 4 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A55717Billing and Coding: Lab: Flow Cytometry
  • A56464Billing and Coding: Flow Cytometry
  • A56718Billing and Coding: Intravenous Immunoglobulin (IVIG)
  • A57689Billing and Coding: Lab: Flow Cytometry

How D58.2 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to D58.2.

  • Heinz body anemia, congenital
  • Hemoglobinopathy(mixed)
  • Abnormal, abnormality, abnormalitieshemoglobin(disease)
  • AnemiaHeinz body, congenital
  • HemoglobinConstant Spring
  • AnemiacongenitalHeinz body
  • Arthritis, arthriticinhemoglobinopathy NEC
  • Arthropathyinhemoglobinopathy NEC
  • Disease, diseasedhemoglobin or Hbabnormal NEC(mixed)
  • Disease, diseasedhemoglobin or HbC(Hb-C)
  • Disease, diseasedhemoglobin or HbConstant Spring
  • Disease, diseasedhemoglobin or HbD(Hb-D)

Related codes at this level

Codes that share D58. If D58.2 is not quite right, the correct code is usually one of these.

Questions about D58.2

Is D58.2 a billable ICD-10-CM code?
Yes. D58.2 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does D58.2 sit in the tabular list?
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89), in the block Hemolytic anemias (D55-D59).
What cannot be coded together with D58.2?
D58.2 carries an Excludes1 note, which means the conditions it lists can never be coded together with it on the same encounter.
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.