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D58.2

D58.2: Other hemoglobinopathies

Billable / specific codeICD-10-CM

D58.2 is a billable, specific ICD-10-CM code for other hemoglobinopathies. It is valid for submission on a claim.

Check D58.2 with the rest of the claim: free scrubber

Excludes1: never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • familial polycythemia (D75.0)
  • Hb-M disease (D74.0)
  • hemoglobin E-beta thalassemia (D56.5)
  • hereditary persistence of fetal hemoglobin [HPFH] (D56.4)
  • high-altitude polycythemia (D75.1)
  • methemoglobinemia (D74.-)
  • other hemoglobinopathies with thalassemia (D56.8)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Abnormal hemoglobin NOS
  • Congenital Heinz body anemia
  • Hb-C disease
  • Hb-D disease
  • Hb-E disease
  • Hemoglobinopathy NOS
  • Unstable hemoglobin hemolytic disease

Excludes1 inherited from the categories above D58.2

A category’s note binds every code beneath it.

Written on D58: Other hereditary hemolytic anemias

  • hemolytic anemia of the newborn (P55.-)

Other codes that can never be billed with D58.2

Their own Excludes1 notes name this code, so the conflict is not listed above.

  • D56.5Hemoglobin E-beta thalassemia
  • D56.8Other thalassemias
  • D57Sickle-cell disorders

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

D58.2 is named in 4 Medicare coverage policies: 4 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A55717Billing and Coding: Lab: Flow Cytometry
  • A56464Billing and Coding: Flow Cytometry
  • A56718Billing and Coding: Intravenous Immunoglobulin (IVIG)
  • A57689Billing and Coding: Lab: Flow Cytometry

Alphabetic index entries that lead here

  • Heinz body anemia, congenital
  • Hemoglobinopathy(mixed)
  • Abnormal, abnormality, abnormalities›hemoglobin(disease)
  • Anemia›Heinz body, congenital
  • Hemoglobin›Constant Spring
  • Anemia›congenital›Heinz body
  • Arthritis, arthritic›in›hemoglobinopathy NEC
  • Arthropathy›in›hemoglobinopathy NEC
  • Disease, diseased›hemoglobin or Hb›abnormal NEC(mixed)
  • Disease, diseased›hemoglobin or Hb›C(Hb-C)
  • Disease, diseased›hemoglobin or Hb›Constant Spring
  • Disease, diseased›hemoglobin or Hb›D(Hb-D)

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under D58

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.