MCMCB Pro
D57.42

D57.42Sickle-cell thalassemia beta zero without crisis

Billable / specific codeICD-10-CM

D57.42 is a billable, specific ICD-10-CM code for sickle-cell thalassemia beta zero without crisis. It is valid for submission on a claim.

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • HbS-beta zero without crisis
  • Sickle-cell beta zero without crisis

Risk adjustment

D57.42 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:

  • HCC 107 Sickle Cell Anemia (Hb-SS) and Thalassemia Beta Zero0.457 RAF

Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score.

Medicare coverage

D57.42 is named in 13 Medicare coverage policies 13 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A55717Billing and Coding: Lab: Flow Cytometry
  • A56421Billing and Coding: CT of the Abdomen and Pelvis
  • A56464Billing and Coding: Flow Cytometry
  • A56580Billing and Coding: Computerized Axial Tomography (CT), Thorax

How D57.42 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to D57.42.

  • Disease, diseasedhemoglobin or HbS or SSbeta zero
  • Disease, diseasedsickle-cellthalassemiabeta zero
  • Disease, diseasedhemoglobin or HbS or SSbeta zerowithout crisis
  • Disease, diseasedsickle-cellthalassemiabeta zerowithout crisis

Related codes at this level

Codes that share D57.4. If D57.42 is not quite right, the correct code is usually one of these.

Questions about D57.42

Is D57.42 a billable ICD-10-CM code?
Yes. D57.42 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does D57.42 sit in the tabular list?
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89), in the block Hemolytic anemias (D55-D59).
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.