MCMCB Pro
D57.40

D57.40Sickle-cell thalassemia without crisis

Billable / specific codeICD-10-CM

D57.40 is a billable, specific ICD-10-CM code for sickle-cell thalassemia without crisis. It is valid for submission on a claim.

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Microdrepanocytosis
  • Sickle-cell thalassemia NOS

Risk adjustment

D57.40 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:

  • HCC 108 Sickle Cell Disorders, Except Sickle Cell Anemia (Hb-SS) and Thalassemia Beta Zero; Beta Thalassemia Major0.146 RAF

Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score.

Medicare coverage

D57.40 is named in 9 Medicare coverage policies 9 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A56580Billing and Coding: Computerized Axial Tomography (CT), Thorax
  • A56697Billing and Coding: Non-Invasive Vascular Studies
  • A56758Billing and Coding: Non-Invasive Vascular Studies
  • A57110Billing and Coding: MolDX: Blood Product Molecular Antigen Typing

How D57.40 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to D57.40.

  • Microdrepanocytosis
  • Anemiamicrodrepanocytosis
  • Disease, diseasedsickle-cellthalassemia
  • Hemoglobinopathysickle-cellwith thalassemia
  • Disease, diseasedsickle-cellthalassemiawithout crisis
  • Hemoglobinopathysickle-cellwith thalassemiawithout crisis

Related codes at this level

Codes that share D57.4. If D57.40 is not quite right, the correct code is usually one of these.

Questions about D57.40

Is D57.40 a billable ICD-10-CM code?
Yes. D57.40 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does D57.40 sit in the tabular list?
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89), in the block Hemolytic anemias (D55-D59).
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.