MCMCB Pro
D55

D55Anemia due to enzyme disorders

Non-billable headerICD-10-CM

D55 is a non-billable header ICD-10-CM code for anemia due to enzyme disorders. It cannot be billed on its own: choose one of the more specific child codes below.

Excludes1 — never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • drug-induced enzyme deficiency anemia (D59.2)

Other codes that can never be billed with D55

These codes carry an Excludes1 note pointing at D55. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading D55 alone.

  • D75.AGlucose-6-phosphate dehydrogenase (G6PD) deficiency without anemia
  • E74.4Disorders of pyruvate metabolism and gluconeogenesis

Risk adjustment

D55 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Code to one of these instead D55

6 child codes. Green means billable.

Questions about D55

Is D55 a billable ICD-10-CM code?
No. D55 is a non-billable header code. Code to a higher level of specificity using one of its child codes.
Where does D55 sit in the tabular list?
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89), in the block Hemolytic anemias (D55-D59).
What cannot be coded together with D55?
D55 carries an Excludes1 note, which means the conditions it lists can never be coded together with it on the same encounter.
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.