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D49

D49Neoplasms of unspecified behavior

Non-billable headerICD-10-CM

D49 is a non-billable header ICD-10-CM code for neoplasms of unspecified behavior. It cannot be billed on its own: choose one of the more specific child codes below.

Excludes2 — not included here, but may coexist

The excluded condition is not part of this code, but a patient can have both. You may code both.

  • neoplasms of uncertain behavior (D37-D44, D48)

Includes

Conditions this code covers.

  • 'growth' NOS
  • neoplasm NOS
  • new growth NOS
  • tumor NOS

Notes

Additional guidance from the ICD-10-CM tabular list.

  • Category D49 classifies by site neoplasms of unspecified morphology and behavior. The term 'mass', unless otherwise stated, is not to be regarded as a neoplastic growth.

Other codes that can never be billed with D49

These codes carry an Excludes1 note pointing at D49. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading D49 alone.

  • C69.2Malignant neoplasm of retina
  • D49.3Neoplasm of unspecified behavior of breast
  • D31.2Benign neoplasm of retina
  • D49.0Neoplasm of unspecified behavior of digestive system
  • D49.2Neoplasm of unspecified behavior of bone, soft tissue, and skin
  • D49.6Neoplasm of unspecified behavior of brain
  • D49.7Neoplasm of unspecified behavior of endocrine glands and other parts of nervous system
  • D49.8Neoplasm of unspecified behavior of other specified sites

Risk adjustment

D49 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Code to one of these instead D49

10 child codes. Green means billable.

Questions about D49

Is D49 a billable ICD-10-CM code?
No. D49 is a non-billable header code. Code to a higher level of specificity using one of its child codes.
Where does D49 sit in the tabular list?
Neoplasms (C00-D49), in the block Neoplasms of unspecified behavior (D49).
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.