MCMedicalCodingSoftware
D49.1

D49.1: Neoplasm of unspecified behavior of respiratory system

Billable / specific codeICD-10-CM

D49.1 is a billable, specific ICD-10-CM code for neoplasm of unspecified behavior of respiratory system. It is valid for submission on a claim.

Check D49.1 with the rest of the claim: free scrubber

Excludes2 inherited from the categories above D49.1

Not part of this code, but both may be coded when both are present.

Written on D49: Neoplasms of unspecified behavior

  • neoplasms of uncertain behavior (D37-D44, D48)

Other codes that can never be billed with D49.1

Their own Excludes1 notes name this code, so the conflict is not listed above.

  • D49.2Neoplasm of unspecified behavior of bone, soft tissue, and skin

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

D49.1 is named in 16 Medicare coverage policies: 16 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A52450Billing and Coding: Paclitaxel (e.g., Taxol®/Abraxane ™)
  • A52480Oral Antiemetic Drugs (Replacement for Intravenous Antiemetics) - Policy Article
  • A52986Billing and Coding: Biomarkers for Oncology
  • A53101Billing and Coding: MolDX: bioTheranostics Cancer TYPE ID® Update

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under D49

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.