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D49.4

D49.4Neoplasm of unspecified behavior of bladder

Billable / specific codeICD-10-CM

D49.4 is a billable, specific ICD-10-CM code for neoplasm of unspecified behavior of bladder. It is valid for submission on a claim.

Excludes2 inherited from the categories above D49.4

Also inherited, and the opposite of Excludes1: these conditions are not part of D49.4, but a patient can have both, so you may code both.

Written on D49 Neoplasms of unspecified behavior

  • neoplasms of uncertain behavior (D37-D44, D48)

Risk adjustment

D49.4 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Medicare coverage

D49.4 is named in 23 Medicare coverage policies 23 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A52986Billing and Coding: Biomarkers for Oncology
  • A53095Billing and Coding: Lab: Bladder/Urothelial Tumor Markers
  • A53101Billing and Coding: MolDX: bioTheranostics Cancer TYPE ID® Update
  • A54188Billing and Coding: MolDX: bioTheranostics Cancer TYPE ID®

Code history

D49.4 has not changed since FY2024 — no addition, revision or deletion across the three most recent ICD-10-CM releases.

Related codes at this level

Codes that share D49. If D49.4 is not quite right, the correct code is usually one of these.

Questions about D49.4

Is D49.4 a billable ICD-10-CM code?
Yes. D49.4 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does D49.4 sit in the tabular list?
Neoplasms (C00-D49), in the block Neoplasms of unspecified behavior (D49).
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.