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D49.9

D49.9Neoplasm of unspecified behavior of unspecified site

Billable / specific codeICD-10-CM

D49.9 is a billable, specific ICD-10-CM code for neoplasm of unspecified behavior of unspecified site. It is valid for submission on a claim.

Risk adjustment

D49.9 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Medicare coverage

D49.9 is named in 10 Medicare coverage policies 10 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A52450Billing and Coding: Paclitaxel (e.g., Taxol®/Abraxane ™)
  • A52986Billing and Coding: Biomarkers for Oncology
  • A53101Billing and Coding: MolDX: bioTheranostics Cancer TYPE ID® Update
  • A54188Billing and Coding: MolDX: bioTheranostics Cancer TYPE ID®

How D49.9 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to D49.9.

  • Dermatomyositisin neoplastic disease(due to)
  • Dermatopolymyositisin neoplastic disease
  • Neuromyopathyparaneoplastic(see also, Neoplasm, by site, if known)
  • Neuropathy, neuropathicparaneoplastic(sensorial) (Denny Brown) (see also, Neoplasm, by site, if known)
  • Arthropathyinneoplastic disease NOS(see also Neoplasm)
  • Encephalopathyinneoplastic disease(see also Neoplasm)
  • Myelopathyinneoplastic disease
  • Polyneuropathyinneoplastic disease
  • Ataxia, ataxy, ataxiccerebellarinneoplastic disease
  • Atrophy, atrophicsystemic affecting central nervous systeminneoplastic disease
  • Compressionnerveroot or plexus NOSneoplastic disease
  • Myastheniasyndromeinneoplastic disease

Related codes at this level

Codes that share D49. If D49.9 is not quite right, the correct code is usually one of these.

Questions about D49.9

Is D49.9 a billable ICD-10-CM code?
Yes. D49.9 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does D49.9 sit in the tabular list?
Neoplasms (C00-D49), in the block Neoplasms of unspecified behavior (D49).
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.