MCMedicalCodingSoftware
D49.9

D49.9: Neoplasm of unspecified behavior of unspecified site

Billable / specific codeICD-10-CM

D49.9 is a billable, specific ICD-10-CM code for neoplasm of unspecified behavior of unspecified site. It is valid for submission on a claim.

Check D49.9 with the rest of the claim: free scrubber

Excludes2 inherited from the categories above D49.9

Not part of this code, but both may be coded when both are present.

Written on D49: Neoplasms of unspecified behavior

  • neoplasms of uncertain behavior (D37-D44, D48)

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

D49.9 is named in 9 Medicare coverage policies: 9 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A52450Billing and Coding: Paclitaxel (e.g., Taxol®/Abraxane ™)
  • A52986Billing and Coding: Biomarkers for Oncology
  • A53101Billing and Coding: MolDX: bioTheranostics Cancer TYPE ID® Update
  • A54188Billing and Coding: MolDX: bioTheranostics Cancer TYPE ID®

Alphabetic index entries that lead here

  • Dermatomyositis›in neoplastic disease(due to)
  • Dermatopolymyositis›in neoplastic disease
  • Neuromyopathy›paraneoplastic(see also, Neoplasm, by site, if known)
  • Neuropathy, neuropathic›paraneoplastic(sensorial) (Denny Brown) (see also, Neoplasm, by site, if known)
  • Arthropathy›in›neoplastic disease NOS(see also Neoplasm)
  • Encephalopathy›in›neoplastic disease(see also Neoplasm)
  • Myelopathy›in›neoplastic disease
  • Polyneuropathy›in›neoplastic disease
  • Ataxia, ataxy, ataxic›cerebellar›in›neoplastic disease
  • Atrophy, atrophic›systemic affecting central nervous system›in›neoplastic disease
  • Compression›nerve›root or plexus NOS›neoplastic disease
  • Myasthenia›syndrome›in›neoplastic disease

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under D49

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.