Is Z16.29 a billable ICD-10-CM code?

Yes. Z16.29 is a billable, specific ICD-10-CM code and is valid for submission on a claim.

Where does Z16.29 sit in the tabular list?

Factors influencing health status and contact with health services (Z00-Z99), in the block Resistance to antimicrobial drugs (Z16).

What cannot be coded together with Z16.29?

Z16.29 carries Excludes1 notes, which means the conditions they list can never be coded together with it on the same encounter. Some are written on the categories above Z16.29 (Z16) and apply to it just the same.

Z16.29

Z16.29 — Resistance to other single specified antibiotic

Billable / specific codeICD-10-CM

Z16.29 is a billable, specific ICD-10-CM code for resistance to other single specified antibiotic. It is valid for submission on a claim.

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

Resistance to aminoglycosides
Resistance to macrolides
Resistance to sulfonamides
Resistance to tetracyclines

Excludes1 inherited from the categories above Z16.29

These are not written on Z16.29, but they bind it: a note on a category applies to every code beneath it. Billing Z16.29 with anything listed here is a denial.

Written on Z16 — Resistance to antimicrobial drugs

Methicillin resistant Staphylococcus aureus infection (A49.02)
Methicillin resistant Staphylococcus aureus pneumonia (J15.212)
Sepsis due to Methicillin resistant Staphylococcus aureus (A41.02)

Risk adjustment

Z16.29 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

How Z16.29 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to Z16.29.

Resistance, resistant›organism›to›drug›aminoglycosides
Resistance, resistant›organism›to›drug›macrolides
Resistance, resistant›organism›to›drug›sulfonamides
Resistance, resistant›organism›to›drug›tetracyclines
Resistance, resistant›organism›to›drug›antibiotic›specified NEC

Code history

Z16.29 has not changed since FY2024 — no addition, revision or deletion across the three most recent ICD-10-CM releases.

Related codes at this level

Codes that share Z16.2. If Z16.29 is not quite right, the correct code is usually one of these.

Questions about Z16.29

Is Z16.29 a billable ICD-10-CM code?: Yes. Z16.29 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does Z16.29 sit in the tabular list?: Factors influencing health status and contact with health services (Z00-Z99), in the block Resistance to antimicrobial drugs (Z16).
What cannot be coded together with Z16.29?: Z16.29 carries Excludes1 notes, which means the conditions they list can never be coded together with it on the same encounter. Some are written on the categories above Z16.29 (Z16) and apply to it just the same.