E75.22 — Gaucher disease
E75.22 is a billable, specific ICD-10-CM code for gaucher disease. It is valid for submission on a claim.
Excludes1 inherited from the categories above E75.22
These are not written on E75.22, but they bind it: a note on a category applies to every code beneath it. Billing E75.22 with anything listed here is a denial.
Other codes that can never be billed with E75.22
These codes carry an Excludes1 note pointing at E75.22. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading E75.22 alone.
- R79Other abnormal findings of blood chemistry
Risk adjustment
E75.22 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:
- HCC 49 Specified Lysosomal Storage Disorders9.256 RAF
Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score.
Medicare coverage
E75.22 is named in 17 Medicare coverage policies — 17 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.
- A52996Billing and Coding: Routine Foot Care
- A56232Billing and Coding: Foot Care
- A56943Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment
- A57037Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment
How E75.22 is indexed
Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to E75.22.
- Cerebroside lipidosis
- Gaucher's disease or splenomegaly(adult) (infantile)
- Lipidosis›cerebroside
- Splenomegaly, splenomegalia›Gaucher's
- Degeneration, degenerative›brain›in›Gaucher's disease
Code history
E75.22 has not changed since FY2024 — no addition, revision or deletion across the three most recent ICD-10-CM releases.
Related codes at this level
Codes that share E75.2. If E75.22 is not quite right, the correct code is usually one of these.
Questions about E75.22
- Is E75.22 a billable ICD-10-CM code?
- Yes. E75.22 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
- Where does E75.22 sit in the tabular list?
- Endocrine, nutritional and metabolic diseases (E00-E89), in the block Metabolic disorders (E70-E88).
- What cannot be coded together with E75.22?
- E75.22 carries Excludes1 notes, which means the conditions they list can never be coded together with it on the same encounter. Some are written on the categories above E75.22 (E75.2, E75) and apply to it just the same.