MCMedicalCodingSoftware
E75.22

E75.22: Gaucher disease

Billable / specific codeICD-10-CM

E75.22 is a billable, specific ICD-10-CM code for gaucher disease. It is valid for submission on a claim.

Check E75.22 with the rest of the claim: free scrubber

Excludes1 inherited from the categories above E75.22

A category’s note binds every code beneath it.

Written on E75.2: Other sphingolipidosis

  • adrenoleukodystrophy [Addison-Schilder] (E71.528)

Written on E75: Disorders of sphingolipid metabolism and other lipid storage disorders

Other codes that can never be billed with E75.22

Their own Excludes1 notes name this code, so the conflict is not listed above.

  • R79Other abnormal findings of blood chemistry

Risk adjustment

E75.22 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:

  • HCC 49 Specified Lysosomal Storage Disorders9.256 RAF

Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score. Look up the whole chart to see which of its HCCs the hierarchy would zero.

Medicare coverage

E75.22 is named in 13 Medicare coverage policies: 13 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A52996Billing and Coding: Routine Foot Care
  • A56232Billing and Coding: Foot Care
  • A56943Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment
  • A57037Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment

Alphabetic index entries that lead here

  • Cerebroside lipidosis
  • Gaucher's disease or splenomegaly(adult) (infantile)
  • Lipidosis›cerebroside
  • Splenomegaly, splenomegalia›Gaucher's
  • Degeneration, degenerative›brain›in›Gaucher's disease

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under E75.2

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.