E75.21 — Fabry (-Anderson) disease
E75.21 is a billable, specific ICD-10-CM code for fabry (-anderson) disease. It is valid for submission on a claim.
Risk adjustment
E75.21 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:
- HCC 49 Specified Lysosomal Storage Disorders9.256 RAF
Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score.
Medicare coverage
E75.21 is named in 16 Medicare coverage policies — 16 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.
- A52996Billing and Coding: Routine Foot Care
- A56232Billing and Coding: Foot Care
- A56680Billing and Coding: Routine Foot Care
- A56943Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment
How E75.21 is indexed
Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to E75.21.
- Anderson-Fabry disease
- Fabry disease(-Anderson)
- Sweeley-Klionsky disease
- Angiokeratoma›corporis diffusum
- Disease, diseased›Sweeley-Klionsky
- Lipidosis›glycolipid
- Disorder›glomerular›Fabry's disease
- Glomerulonephritis›in›Fabry disease(-Anderson)
- Degeneration, degenerative›brain›in›Fabry-Anderson disease
Related codes at this level
Codes that share E75.2. If E75.21 is not quite right, the correct code is usually one of these.
Questions about E75.21
- Is E75.21 a billable ICD-10-CM code?
- Yes. E75.21 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
- Where does E75.21 sit in the tabular list?
- Endocrine, nutritional and metabolic diseases (E00-E89), in the block Metabolic disorders (E70-E88).