E77.0 — Defects in post-translational modification of lysosomal enzymes
E77.0 is a billable, specific ICD-10-CM code for defects in post-translational modification of lysosomal enzymes. It is valid for submission on a claim.
Inclusion terms
Alternative wordings a physician may use in the chart for this same code.
- Mucolipidosis II [I-cell disease]
- Mucolipidosis III [pseudo-Hurler polydystrophy]
Other codes that can never be billed with E77.0
These codes carry an Excludes1 note pointing at E77.0. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading E77.0 alone.
- E75Disorders of sphingolipid metabolism and other lipid storage disorders
Risk adjustment
E77.0 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.
Medicare coverage
E77.0 is named in 13 Medicare coverage policies — 13 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.
- A52996Billing and Coding: Routine Foot Care
- A56232Billing and Coding: Foot Care
- A56943Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment
- A57037Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment
How E77.0 is indexed
Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to E77.0.
- Polydystrophy, pseudo-Hurler
- Pseudo-Hurler's polydystrophy
- Defect, defective›lysosomal enzyme, post-translational modification
- Defect, defective›modification, lysosomal enzymes, post-translational
- Disease, diseased›I-cell
- Disease, diseased›pseudo-Hurler's
- Mucolipidosis›II, III
Related codes at this level
Codes that share E77. If E77.0 is not quite right, the correct code is usually one of these.
Questions about E77.0
- Is E77.0 a billable ICD-10-CM code?
- Yes. E77.0 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
- Where does E77.0 sit in the tabular list?
- Endocrine, nutritional and metabolic diseases (E00-E89), in the block Metabolic disorders (E70-E88).