MCMedicalCodingSoftware
E72.11

E72.11: Homocystinuria

Billable / specific codeICD-10-CM

E72.11 is a billable, specific ICD-10-CM code for homocystinuria. It is valid for submission on a claim.

Check E72.11 with the rest of the claim: free scrubber

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Cystathionine synthase deficiency

Excludes1 inherited from the categories above E72.11

A category’s note binds every code beneath it.

Written on E72.1: Disorders of sulfur-bearing amino-acid metabolism

Written on E72: Other disorders of amino-acid metabolism

  • disorders of:
  • aromatic amino-acid metabolism (E70.-)
  • branched-chain amino-acid metabolism (E71.0-E71.2)
  • fatty-acid metabolism (E71.3)
  • purine and pyrimidine metabolism (E79.-)
  • gout (M1A.-, M10.-)

Other codes that can never be billed with E72.11

Their own Excludes1 notes name this code, so the conflict is not listed above.

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

E72.11 is named in 1 Medicare coverage policy: 1 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A56416Billing and Coding: Assays for Vitamins and Metabolic Function

Alphabetic index entries that lead here

  • Cystathionine synthase deficiency
  • Homocystinuria
  • Hyperhomocysteinemia
  • Disorder›amino-acid›homocystinuria
  • Disorder›metabolism NOS›amino-acid›sulfur-bearing›homocystinuria

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under E72.1

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.