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E27.49

E27.49: Other adrenocortical insufficiency

Billable / specific codeICD-10-CM

E27.49 is a billable, specific ICD-10-CM code for other adrenocortical insufficiency. It is valid for submission on a claim.

Check E27.49 with the rest of the claim: free scrubber

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Adrenal hemorrhage
  • Adrenal infarction

Excludes1 inherited from the categories above E27.49

A category’s note binds every code beneath it.

Written on E27.4: Other and unspecified adrenocortical insufficiency

  • adrenoleukodystrophy [Addison-Schilder] (E71.528)
  • Waterhouse-Friderichsen syndrome (A39.1)

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

E27.49 is named in 3 Medicare coverage policies: 3 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A57326Billing and Coding: Electrocardiograms
  • A57361Billing and Coding: Monitored Anesthesia Care
  • A59186Billing and Coding: Magnesium

Alphabetic index entries that lead here

  • Atrophy, atrophic›adrenal(capsule) (gland)
  • Atrophy, atrophic›suprarenal(capsule) (gland)
  • Calcification›adrenal(capsule) (gland)
  • Calcification›suprarenal(capsule) (gland)
  • Deficiency, deficient›combined glucocorticoid and mineralocorticoid
  • Deficiency, deficient›glucocorticoid
  • Deficiency, deficient›mineralocorticoid
  • Hemorrhage, hemorrhagic›adrenal(capsule) (gland)
  • Hemorrhage, hemorrhagic›suprarenal(capsule) (gland)
  • Infarct, infarction›adrenal(capsule) (gland)
  • Infarct, infarction›suprarenal(capsule) (gland)
  • Insensitivity›adrenocorticotropin hormone(ACTH)

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under E27.4

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.