MCMedicalCodingSoftware
E27.40

E27.40Unspecified adrenocortical insufficiency

Billable / specific codeICD-10-CM

E27.40 is a billable, specific ICD-10-CM code for unspecified adrenocortical insufficiency. It is valid for submission on a claim.

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Adrenocortical insufficiency NOS
  • Hypoaldosteronism

Excludes1 inherited from the categories above E27.40

These are not written on E27.40, but they bind it: a note on a category applies to every code beneath it. Billing E27.40 with anything listed here is a denial.

Written on E27.4 Other and unspecified adrenocortical insufficiency

  • adrenoleukodystrophy [Addison-Schilder] (E71.528)
  • Waterhouse-Friderichsen syndrome (A39.1)

Risk adjustment

E27.40 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Medicare coverage

E27.40 is named in 2 Medicare coverage policies 2 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A57361Billing and Coding: Monitored Anesthesia Care
  • A59186Billing and Coding: Magnesium

How E27.40 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to E27.40.

  • Hypoadrenalism, hypoadrenia
  • Hypoadrenocorticism
  • Hypoaldosteronism
  • Deficiency, deficientcorticoadrenal
  • Hypofunctionadrenocortical
  • Hypofunctioncorticoadrenal NEC
  • Insufficiency, insufficientadrenal(gland)
  • Insufficiency, insufficientadrenocortical
  • Insufficiency, insufficientcorticoadrenal
  • Insufficiency, insufficientsuprarenal

Code history

E27.40 has not changed since FY2024 — no addition, revision or deletion across the three most recent ICD-10-CM releases.

Related codes at this level

Codes that share E27.4. If E27.40 is not quite right, the correct code is usually one of these.

Questions about E27.40

Is E27.40 a billable ICD-10-CM code?
Yes. E27.40 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does E27.40 sit in the tabular list?
Endocrine, nutritional and metabolic diseases (E00-E89), in the block Disorders of other endocrine glands (E20-E35).
What cannot be coded together with E27.40?
E27.40 carries Excludes1 notes, which means the conditions they list can never be coded together with it on the same encounter. Some are written on the categories above E27.40 (E27.4) and apply to it just the same.
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.