MCMedicalCodingSoftware
E21.5

E21.5: Disorder of parathyroid gland, unspecified

Billable / specific codeICD-10-CM

E21.5 is a billable, specific ICD-10-CM code for disorder of parathyroid gland, unspecified. It is valid for submission on a claim.

Check E21.5 with the rest of the claim: free scrubber

Excludes1 inherited from the categories above E21.5

A category’s note binds every code beneath it.

Written on E21: Hyperparathyroidism and other disorders of parathyroid gland

  • adult osteomalacia (M83.-)
  • ectopic hyperparathyroidism (E34.2)
  • hungry bone syndrome (E83.81)
  • infantile and juvenile osteomalacia (E55.0)

Excludes2 inherited from the categories above E21.5

Not part of this code, but both may be coded when both are present.

Written on E21: Hyperparathyroidism and other disorders of parathyroid gland

  • familial hypocalciuric hypercalcemia (E83.52)

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

E21.5 is named in 2 Medicare coverage policies: 2 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A57361Billing and Coding: Monitored Anesthesia Care
  • A57484Billing and Coding: Vitamin D Assay Testing

Alphabetic index entries that lead here

  • Disease, diseased›parathyroid(gland)
  • Disorder›parathyroid(gland)

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under E21

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.