E16.3 — Increased secretion of glucagon
E16.3 is a billable, specific ICD-10-CM code for increased secretion of glucagon. It is valid for submission on a claim.
Inclusion terms
Alternative wordings a physician may use in the chart for this same code.
- Hyperplasia of pancreatic endocrine cells with glucagon excess
Other codes that can never be billed with E16.3
These codes carry an Excludes1 note pointing at E16.3. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading E16.3 alone.
- E74Other disorders of carbohydrate metabolism
Risk adjustment
E16.3 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.
Medicare coverage
E16.3 is named in 2 Medicare coverage policies — 2 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.
- A56421Billing and Coding: CT of the Abdomen and Pelvis
- A57361Billing and Coding: Monitored Anesthesia Care
How E16.3 is indexed
Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to E16.3.
- Abnormal, abnormality, abnormalities›glucagon secretion
- Excess, excessive, excessively›glucagon
- Hypersecretion›glucagon
- Abnormal, abnormality, abnormalities›secretion›glucagon
- Increase, increased›secretion›glucagon
- Hyperplasia, hyperplastic›pancreatic islet cells›alpha›with excess›glucagon
Related codes at this level
Codes that share E16. If E16.3 is not quite right, the correct code is usually one of these.
Questions about E16.3
- Is E16.3 a billable ICD-10-CM code?
- Yes. E16.3 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
- Where does E16.3 sit in the tabular list?
- Endocrine, nutritional and metabolic diseases (E00-E89), in the block Other disorders of glucose regulation and pancreatic internal secretion (E15-E16).