MCMedicalCodingSoftware
E16.3

E16.3: Increased secretion of glucagon

Billable / specific codeICD-10-CM

E16.3 is a billable, specific ICD-10-CM code for increased secretion of glucagon. It is valid for submission on a claim.

Check E16.3 with the rest of the claim: free scrubber

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Hyperplasia of pancreatic endocrine cells with glucagon excess

Other codes that can never be billed with E16.3

Their own Excludes1 notes name this code, so the conflict is not listed above.

  • E74Other disorders of carbohydrate metabolism

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

E16.3 is named in 2 Medicare coverage policies: 2 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A56421Billing and Coding: CT of the Abdomen and Pelvis
  • A57361Billing and Coding: Monitored Anesthesia Care

Alphabetic index entries that lead here

  • Abnormal, abnormality, abnormalities›glucagon secretion
  • Excess, excessive, excessively›glucagon
  • Hypersecretion›glucagon
  • Abnormal, abnormality, abnormalities›secretion›glucagon
  • Increase, increased›secretion›glucagon
  • Hyperplasia, hyperplastic›pancreatic islet cells›alpha›with excess›glucagon

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under E16

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.