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D82.4

D82.4: Hyperimmunoglobulin E [IgE] syndrome

Billable / specific codeICD-10-CM

D82.4 is a billable, specific ICD-10-CM code for hyperimmunoglobulin e [ige] syndrome. It is valid for submission on a claim.

Check D82.4 with the rest of the claim: free scrubber

Excludes1 inherited from the categories above D82.4

A category’s note binds every code beneath it.

Written on D82: Immunodeficiency associated with other major defects

  • ataxia telangiectasia [Louis-Bar] (G11.3)

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

D82.4 is named in 21 Medicare coverage policies: 21 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A52507External Infusion Pumps - Policy Article
  • A52509Intravenous Immune Globulin - Policy Article
  • A54660Billing and Coding: Coverage of Intravenous Immune Globulin for Treatment of Primary Immune Deficiency Diseases in the Home – Medicare Benefit Policy Manual, Chapter 15, 50.6
  • A56638Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs)

Alphabetic index entries that lead here

  • Syndrome›hyperimmunoglobulin E(IgE)

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under D82

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.