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D59.6

D59.6: Hemoglobinuria due to hemolysis from other external causes

Billable / specific codeICD-10-CM

D59.6 is a billable, specific ICD-10-CM code for hemoglobinuria due to hemolysis from other external causes. It is valid for submission on a claim.

Check D59.6 with the rest of the claim: free scrubber

Excludes1: never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • hemoglobinuria NOS (R82.3)

Use additional code

Add a secondary code to capture the detail described below.

  • code (Chapter 20) to identify external cause

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Hemoglobinuria from exertion
  • March hemoglobinuria
  • Paroxysmal cold hemoglobinuria

Other codes that can never be billed with D59.6

Their own Excludes1 notes name this code, so the conflict is not listed above.

Risk adjustment

D59.6 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:

  • HCC 109 Acquired Hemolytic, Aplastic, and Sideroblastic Anemias1.144 RAF

Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score. Look up the whole chart to see which of its HCCs the hierarchy would zero.

Medicare coverage

D59.6 is named in 3 Medicare coverage policies: 3 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A55717Billing and Coding: Lab: Flow Cytometry
  • A56464Billing and Coding: Flow Cytometry
  • A57689Billing and Coding: Lab: Flow Cytometry

Alphabetic index entries that lead here

  • Harley's disease
  • Murri's disease(intermittent hemoglobinuria)
  • Hemoglobinemia›paroxysmal
  • Hemoglobinuria›cold(paroxysmal) (with Raynaud's syndrome)
  • Hemoglobinuria›due to exertion or hemolysis NEC
  • Hemoglobinuria›intermittent
  • Hemoglobinuria›march
  • Hemoglobinuria›paroxysmal(cold)
  • Hemoglobinuria›with anemia, hemolytic, acquired NEC(chronic)
  • March›hemoglobinuria
  • Anemia›hemolytic›acquired›with hemoglobinuria NEC
  • Disease, diseased›cold›agglutinin or hemoglobinuria›paroxysmal

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under D59

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.