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D59.4

D59.4Other nonautoimmune hemolytic anemias

Billable / specific codeICD-10-CM

D59.4 is a billable, specific ICD-10-CM code for other nonautoimmune hemolytic anemias. It is valid for submission on a claim.

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Mechanical hemolytic anemia
  • Microangiopathic hemolytic anemia
  • Toxic hemolytic anemia

Risk adjustment

D59.4 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:

  • HCC 109 Acquired Hemolytic, Aplastic, and Sideroblastic Anemias1.144 RAF

Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score.

Medicare coverage

D59.4 is named in 2 Medicare coverage policies 2 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A59105Billing and Coding: Off-Label Use of Intravenous Immune Globulin (IVIG)
  • A60187Billing and Coding: Off-Label Use of Intravenous Immune Globulin (IVIG)

How D59.4 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to D59.4.

  • Nonautoimmune hemolytic anemia
  • Disease, diseasednonautoimmune hemolytic
  • Syndromeerythrocyte fragmentation
  • Anemiahemolyticmechanical
  • Anemiahemolyticmicroangiopathic
  • Anemiahemolyticnonautoimmune
  • Anemiahemolyticsecondary
  • Anemiahemolyticsymptomatic
  • Anemiahemolytictoxic
  • Anemiahemolyticacquiredinfectious
  • Anemiahemolyticacquiredtoxic
  • Anemiahemolyticdue tocardiac conditions

Related codes at this level

Codes that share D59. If D59.4 is not quite right, the correct code is usually one of these.

Questions about D59.4

Is D59.4 a billable ICD-10-CM code?
Yes. D59.4 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does D59.4 sit in the tabular list?
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89), in the block Hemolytic anemias (D55-D59).
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.