MCMedicalCodingSoftware
D57.431

D57.431: Sickle-cell thalassemia beta zero with acute chest syndrome

Billable / specific codeICD-10-CM

D57.431 is a billable, specific ICD-10-CM code for sickle-cell thalassemia beta zero with acute chest syndrome. It is valid for submission on a claim.

Check D57.431 with the rest of the claim: free scrubber

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • HbS-beta zero with acute chest syndrome
  • Sickle-cell beta zero with acute chest syndrome

Excludes1 inherited from the categories above D57.431

A category’s note binds every code beneath it.

Written on D57: Sickle-cell disorders

  • other hemoglobinopathies (D58.-)

Other codes that can never be billed with D57.431

Their own Excludes1 notes name this code, so the conflict is not listed above.

Risk adjustment

D57.431 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:

  • HCC 107 Sickle Cell Anemia (Hb-SS) and Thalassemia Beta Zero0.457 RAF

Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score. Look up the whole chart to see which of its HCCs the hierarchy would zero.

Medicare coverage

D57.431 is named in 15 Medicare coverage policies: 15 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A55717Billing and Coding: Lab: Flow Cytometry
  • A56464Billing and Coding: Flow Cytometry
  • A56580Billing and Coding: Computerized Axial Tomography (CT), Thorax
  • A56697Billing and Coding: Non-Invasive Vascular Studies

Alphabetic index entries that lead here

  • Disease, diseased›hemoglobin or Hb›S or SS›beta zero›with›acute chest syndrome
  • Disease, diseased›sickle-cell›thalassemia›beta zero›with›acute chest syndrome

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under D57.43

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.