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Z15.06

Z15.06: Genetic susceptibility to malignant neoplasm of digestive system

Non-billable headerICD-10-CM

Z15.06 is a non-billable header ICD-10-CM code for genetic susceptibility to malignant neoplasm of digestive system. It cannot be billed on its own: choose one of the more specific child codes below.

Excludes1 inherited from the categories above Z15.06

A category’s note binds every code beneath it.

Written on Z15: Genetic susceptibility to disease

  • chromosomal anomalies (Q90-Q99)

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Code history

Unchanged in every release from FY2024 to FY2027.

Code to one of these instead Z15.06

2 child codes. Green means billable.

Other codes under Z15.0

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.