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Z15.0

Z15.0: Genetic susceptibility to malignant neoplasm

Non-billable headerICD-10-CM

Z15.0 is a non-billable header ICD-10-CM code for genetic susceptibility to malignant neoplasm. It cannot be billed on its own: choose one of the more specific child codes below.

Code first

The underlying condition must be sequenced before this code.

  • , if applicable, any current malignant neoplasm (C00-C75, C81-C96)

Use additional code

Add a secondary code to capture the detail described below.

  • code, if applicable, for any personal history of malignant neoplasm (Z85.-)

Excludes1 inherited from the categories above Z15.0

A category’s note binds every code beneath it.

Written on Z15: Genetic susceptibility to disease

  • chromosomal anomalies (Q90-Q99)

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Code history

Unchanged in every release from FY2024 to FY2027.

Code to one of these instead Z15.0

8 child codes. Green means billable.

Other codes under Z15

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.