MCMedicalCodingSoftware
Z15.01

Z15.01: Genetic susceptibility to malignant neoplasm of breast

Billable / specific codeICD-10-CMPOA exempt

Z15.01 is a billable, specific ICD-10-CM code for genetic susceptibility to malignant neoplasm of breast. It is valid for submission on a claim.

Check Z15.01 with the rest of the claim: free scrubber

Excludes1 inherited from the categories above Z15.01

A category’s note binds every code beneath it.

Written on Z15: Genetic susceptibility to disease

  • chromosomal anomalies (Q90-Q99)

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

Z15.01 is named in 2 Medicare coverage policies: 2 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A58774Billing and Coding: Cosmetic and Reconstructive Surgery
  • A59299Billing and Coding: Cosmetic and Reconstructive Surgery

Alphabetic index entries that lead here

  • Family, familial›Li-Fraumeni(syndrome)
  • Susceptibility to disease, genetic›malignant neoplasm›breast
  • Genetic›susceptibility to disease NEC›malignant neoplasm›breast

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under Z15.0

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.