MCMCB Pro
T80.82XA

T80.82XAComplication of immune effector cellular therapy, initial encounter

Billable / specific codeICD-10-CM

T80.82XA is a billable, specific ICD-10-CM code for complication of immune effector cellular therapy, initial encounter. It is valid for submission on a claim.

7th character "A" — initial encounter

The appropriate 7th character is to be added to each code from category T80

A
initial encounter
D
subsequent encounter
S
sequela

Excludes2 — not included here, but may coexist

The excluded condition is not part of this code, but a patient can have both. You may code both.

  • adverse effect of immune checkpoint inhibitors and immunostimulant drugs (T45.AX5)
  • complication of bone marrow transplant (T86.0)
  • complication of stem cell transplant (T86.5)

Use additional code

Add a secondary code to capture the detail described below.

  • code to identify the specific complication, such as:
  • cytokine release syndrome (D89.83-)
  • immune effector cell-associated neurotoxicity syndrome (G92.0-)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Complication of chimeric antigen receptor (CAR-T) cell therapy
  • Complication of IEC therapy

Risk adjustment

T80.82XA does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Medicare coverage

T80.82XA is named in 2 Medicare coverage policies 2 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A59105Billing and Coding: Off-Label Use of Intravenous Immune Globulin (IVIG)
  • A60187Billing and Coding: Off-Label Use of Intravenous Immune Globulin (IVIG)

Related codes at this level

Codes that share T80.82. If T80.82XA is not quite right, the correct code is usually one of these.

Questions about T80.82XA

Is T80.82XA a billable ICD-10-CM code?
Yes. T80.82XA is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does T80.82XA sit in the tabular list?
Injury, poisoning and certain other consequences of external causes (S00-T88), in the block Complications of surgical and medical care, not elsewhere classified (T80-T88).
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.