MCMedicalCodingSoftware
T80.82

T80.82: Complication of immune effector cellular therapy

Non-billable headerICD-10-CM

T80.82 is a non-billable header ICD-10-CM code for complication of immune effector cellular therapy. It cannot be billed on its own: choose one of the more specific child codes below. This code also requires a 7th character before it is complete.

This code requires a 7th character

The appropriate 7th character is to be added to each code from category T80

A
initial encounter
D
subsequent encounter
S
sequela

Excludes2: not included here, but may coexist

The excluded condition is not part of this code, but a patient can have both. You may code both.

  • adverse effect of immune checkpoint inhibitors and immunostimulant drugs (T45.AX5)
  • complication of bone marrow transplant (T86.0)
  • complication of stem cell transplant (T86.5)

Use additional code

Add a secondary code to capture the detail described below.

  • code to identify the specific complication, such as:
  • cytokine release syndrome (D89.83-)
  • immune effector cell-associated neurotoxicity syndrome (G92.0-)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Complication of chimeric antigen receptor (CAR-T) cell therapy
  • Complication of IEC therapy

Excludes2 inherited from the categories above T80.82

Not part of this code, but both may be coded when both are present.

Written on T80: Complications following infusion, transfusion and therapeutic injection

  • bone marrow transplant rejection (T86.01)
  • febrile nonhemolytic transfusion reaction (R50.84)
  • fluid overload due to transfusion (E87.71)
  • posttransfusion purpura (D69.51)
  • transfusion associated circulatory overload (TACO) (E87.71)
  • transfusion (red blood cell) associated hemochromatosis (E83.111)
  • transfusion related acute lung injury (TRALI) (J95.84)

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Alphabetic index entries that lead here

  • Complication›chimeric antigen receptor cell therapy(CAR-T)
  • Complication›IEC therapy(immune effector cellular)
  • Complication›immune effector cellular therapy(IEC)

Code history

Unchanged in every release from FY2024 to FY2027.

Code to one of these instead T80.82

3 child codes. Green means billable.

Other codes under T80.8

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.