MCMCB Pro
T80.82

T80.82Complication of immune effector cellular therapy

Non-billable headerICD-10-CM

T80.82 is a non-billable header ICD-10-CM code for complication of immune effector cellular therapy. It cannot be billed on its own: choose one of the more specific child codes below. This code also requires a 7th character before it is complete.

This code requires a 7th character

The appropriate 7th character is to be added to each code from category T80

A
initial encounter
D
subsequent encounter
S
sequela

Excludes2 — not included here, but may coexist

The excluded condition is not part of this code, but a patient can have both. You may code both.

  • adverse effect of immune checkpoint inhibitors and immunostimulant drugs (T45.AX5)
  • complication of bone marrow transplant (T86.0)
  • complication of stem cell transplant (T86.5)

Use additional code

Add a secondary code to capture the detail described below.

  • code to identify the specific complication, such as:
  • cytokine release syndrome (D89.83-)
  • immune effector cell-associated neurotoxicity syndrome (G92.0-)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Complication of chimeric antigen receptor (CAR-T) cell therapy
  • Complication of IEC therapy

Risk adjustment

T80.82 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

How T80.82 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to T80.82.

  • Complicationchimeric antigen receptor cell therapy(CAR-T)
  • ComplicationIEC therapy(immune effector cellular)
  • Complicationimmune effector cellular therapy(IEC)

Code to one of these instead T80.82

3 child codes. Green means billable.

Related codes at this level

Codes that share T80.8. If T80.82 is not quite right, the correct code is usually one of these.

Questions about T80.82

Is T80.82 a billable ICD-10-CM code?
No. T80.82 is a non-billable header code. Code to a higher level of specificity using one of its child codes.
Where does T80.82 sit in the tabular list?
Injury, poisoning and certain other consequences of external causes (S00-T88), in the block Complications of surgical and medical care, not elsewhere classified (T80-T88).
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.