MCMedicalCodingSoftware
T80.69XA

T80.69XAOther serum reaction due to other serum, initial encounter

Billable / specific codeICD-10-CM

T80.69XA is a billable, specific ICD-10-CM code for other serum reaction due to other serum, initial encounter. It is valid for submission on a claim.

7th character "A" — initial encounter

The appropriate 7th character is to be added to each code from category T80

A
initial encounter
D
subsequent encounter
S
sequela

Code also

Both codes may be needed to describe the encounter fully. Sequencing depends on the reason for the visit.

  • , if applicable, arthropathy in hypersensitivity reactions classified elsewhere (M36.4)

Excludes2 inherited from the categories above T80.69XA

Also inherited, and the opposite of Excludes1: these conditions are not part of T80.69XA, but a patient can have both, so you may code both.

Written on T80.6 Other serum reactions

Written on T80 Complications following infusion, transfusion and therapeutic injection

  • bone marrow transplant rejection (T86.01)
  • febrile nonhemolytic transfusion reaction (R50.84)
  • fluid overload due to transfusion (E87.71)
  • posttransfusion purpura (D69.51)
  • transfusion associated circulatory overload (TACO) (E87.71)
  • transfusion (red blood cell) associated hemochromatosis (E83.111)
  • transfusion related acute lung injury (TRALI) (J95.84)

Risk adjustment

T80.69XA does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Medicare coverage

T80.69XA is named in 5 Medicare coverage policies 5 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A56558Billing and Coding: Allergy Testing
  • A56612Billing and Coding: CT of the Head
  • A57473Billing and Coding: Allergy Testing
  • A57473Billing and Coding: Allergy Testing

Code history

T80.69XA has not changed since FY2024 — no addition, revision or deletion across the three most recent ICD-10-CM releases.

Related codes at this level

Codes that share T80.69. If T80.69XA is not quite right, the correct code is usually one of these.

Questions about T80.69XA

Is T80.69XA a billable ICD-10-CM code?
Yes. T80.69XA is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does T80.69XA sit in the tabular list?
Injury, poisoning and certain other consequences of external causes (S00-T88), in the block Complications of surgical and medical care, not elsewhere classified (T80-T88).
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.