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R53.82

R53.82: Chronic fatigue, unspecified

Billable / specific codeICD-10-CM

R53.82 is a billable, specific ICD-10-CM code for chronic fatigue, unspecified. It is valid for submission on a claim.

Check R53.82 with the rest of the claim: free scrubber

Excludes1: never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • chronic fatigue syndrome (G93.32)
  • myalgic encephalomyelitis (G93.32)
  • other post infection and related fatigue syndromes (G93.39)
  • postviral fatigue syndrome (G93.31)

Excludes1 inherited from the categories above R53.82

A category’s note binds every code beneath it.

Written on R53.8: Other malaise and fatigue

  • combat exhaustion and fatigue (F43.0)
  • congenital debility (P96.9)
  • exhaustion and fatigue due to excessive exertion (T73.3)
  • exhaustion and fatigue due to exposure (T73.2)
  • exhaustion and fatigue due to heat (T67.-)
  • exhaustion and fatigue due to pregnancy (O26.8-)
  • exhaustion and fatigue due to recurrent depressive episode (F33-)
  • exhaustion and fatigue due to senile debility (R54)

Other codes that can never be billed with R53.82

Their own Excludes1 notes name this code, so the conflict is not listed above.

  • G93.3Postviral and related fatigue syndromes

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

R53.82 is named in 2 Medicare coverage policies: 2 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A58921Billing and Coding: Mass Spectrometry (MS) Testing in Monoclonal Gammopathy (MG)
  • A59186Billing and Coding: Magnesium

Alphabetic index entries that lead here

  • Fatigue›chronic

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under R53.8

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.