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R53.81

R53.81: Other malaise

Billable / specific codeICD-10-CM

R53.81 is a billable, specific ICD-10-CM code for other malaise. It is valid for submission on a claim.

Check R53.81 with the rest of the claim: free scrubber

Excludes1: never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • age-related physical debility (R54)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Chronic debility
  • Debility NOS
  • General physical deterioration
  • Malaise NOS
  • Nervous debility

Excludes1 inherited from the categories above R53.81

A category’s note binds every code beneath it.

Written on R53.8: Other malaise and fatigue

  • combat exhaustion and fatigue (F43.0)
  • congenital debility (P96.9)
  • exhaustion and fatigue due to excessive exertion (T73.3)
  • exhaustion and fatigue due to exposure (T73.2)
  • exhaustion and fatigue due to heat (T67.-)
  • exhaustion and fatigue due to pregnancy (O26.8-)
  • exhaustion and fatigue due to recurrent depressive episode (F33-)
  • exhaustion and fatigue due to senile debility (R54)

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

R53.81 is named in 10 Medicare coverage policies: 10 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A54969Billing and Coding: Nerve Conduction Studies and Electromyography
  • A56619Billing and Coding: Nerve Conduction Studies and Electromyography
  • A57122Billing and Coding: Parathormone (Parathyroid Hormone)
  • A57189Billing and Coding: Serum Magnesium

Alphabetic index entries that lead here

  • Debility(chronic) (general) (nervous)
  • Malaise
  • Debility›nervous
  • Deterioration›general physical

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under R53.8

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.