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E87.21

E87.21: Acute metabolic acidosis

Billable / specific codeICD-10-CM

E87.21 is a billable, specific ICD-10-CM code for acute metabolic acidosis. It is valid for submission on a claim.

Check E87.21 with the rest of the claim: free scrubber

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Acute lactic acidosis

Excludes1 inherited from the categories above E87.21

A category’s note binds every code beneath it.

Written on E87.2: Acidosis

  • diabetic acidosis - see categories E08-E10, E11, E13 with ketoacidosis

Written on E87: Other disorders of fluid, electrolyte and acid-base balance

  • diabetes insipidus (E23.2)
  • electrolyte imbalance associated with hyperemesis gravidarum (O21.1)
  • electrolyte imbalance following ectopic or molar pregnancy (O08.5)
  • familial periodic paralysis (G72.3)
  • metabolic acidemia in newborn, unspecified (P19.9)

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

E87.21 is named in 17 Medicare coverage policies: 17 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A54799Billing and Coding: Urine Drug Testing
  • A55001Billing and Coding: Urine Drug Testing
  • A55354Billing and Coding: Frequency of Hemodialysis
  • A55672Billing and Coding: Frequency of Hemodialysis

Alphabetic index entries that lead here

  • Acidosis›lactic›acute
  • Acidosis›metabolic NEC›acute
  • Disorder›electrolyte NEC›acidosis›acute

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under E87.2

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.