E83.821 — ENPP1 deficiency causing generalized arterial calcification of infancy
E83.821 is a billable, specific ICD-10-CM code for enpp1 deficiency causing generalized arterial calcification of infancy. It is valid for submission on a claim.
Code also
Both codes may be needed to describe the encounter fully. Sequencing depends on the reason for the visit.
Excludes1 inherited from the categories above E83.821
These are not written on E83.821, but they bind it: a note on a category applies to every code beneath it. Billing E83.821 with anything listed here is a denial.
Other codes that can never be billed with E83.821
These codes carry an Excludes1 note pointing at E83.821. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading E83.821 alone.
Risk adjustment
E83.821 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.
How E83.821 is indexed
Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to E83.821.
- Deficiency, deficient›ENPP1›causing›generalized arterial calcification of infancy
- Calcification›arterial›generalized, of infancy›with›ENPP1 deficiency
Code history
What changed, and when. Derived by diffing consecutive CMS release files — which matters when you are defending a code assigned under an earlier edition.
- addedFY2024-FY2026
ENPP1 deficiency causing generalized arterial calcification of infancy
Related codes at this level
Codes that share E83.82. If E83.821 is not quite right, the correct code is usually one of these.
- E83.820Generalized arterial calcification of infancy with unspecified genetic causality
- E83.822ENPP1 deficiency causing autosomal recessive hypophosphatemic rickets type 2
- E83.823ABCC6 deficiency causing generalized arterial calcification of infancy
- E83.824ABCC6 deficiency causing pseudoxanthoma elasticum
- E83.825CD73 deficiency causing arterial calcification
Questions about E83.821
- Is E83.821 a billable ICD-10-CM code?
- Yes. E83.821 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
- Where does E83.821 sit in the tabular list?
- Endocrine, nutritional and metabolic diseases (E00-E89), in the block Metabolic disorders (E70-E88).
- What cannot be coded together with E83.821?
- E83.821 carries Excludes1 notes, which means the conditions they list can never be coded together with it on the same encounter. Some are written on the categories above E83.821 (E83) and apply to it just the same.