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E80.3

E80.3Defects of catalase and peroxidase

Billable / specific codeICD-10-CM

E80.3 is a billable, specific ICD-10-CM code for defects of catalase and peroxidase. It is valid for submission on a claim.

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Acatalasia [Takahara]

Risk adjustment

E80.3 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:

  • HCC 50 Amyloidosis, Porphyria, and Other Specified Metabolic Disorders0.648 RAF

Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score.

Medicare coverage

E80.3 is named in 1 Medicare coverage policy 1 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A56421Billing and Coding: CT of the Abdomen and Pelvis

How E80.3 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to E80.3.

  • Acatalasemia, acatalasia
  • Takahara's disease
  • Defect, defectivecatalase
  • Defect, defectiveperoxidase
  • Defect, defectiveenzymecatalase
  • Defect, defectiveenzymeperoxidase

Related codes at this level

Codes that share E80. If E80.3 is not quite right, the correct code is usually one of these.

Questions about E80.3

Is E80.3 a billable ICD-10-CM code?
Yes. E80.3 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does E80.3 sit in the tabular list?
Endocrine, nutritional and metabolic diseases (E00-E89), in the block Metabolic disorders (E70-E88).
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.