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E72.81

E72.81Disorders of gamma aminobutyric acid metabolism

Billable / specific codeICD-10-CM

E72.81 is a billable, specific ICD-10-CM code for disorders of gamma aminobutyric acid metabolism. It is valid for submission on a claim.

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • 4-hydroxybutyric aciduria
  • Disorders of GABA metabolism
  • GABA metabolic defect
  • GABA transaminase deficiency
  • GABA-T deficiency
  • Gamma-hydroxybutyric aciduria
  • SSADHD
  • Succinic semialdehyde dehydrogenase deficiency

Risk adjustment

E72.81 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

How E72.81 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to E72.81.

  • SSADHD(succinic semialdehyde dehydrogenase deficiency)
  • Aciduria4-hydroxybutyric
  • Aciduriagamma-hydroxybutyric
  • Defect, defectiveGABA metabolic(gamma aminobutyric acid)
  • Deficiency, deficientGABA transaminase(gamma aminobutyric acid)
  • Deficiency, deficientGABA-T(gamma aminobutyric acid transaminase)
  • Deficiency, deficientsuccinic semialdehyde dehydrogenase
  • Disordergamma aminobutyric acid metabolism(GABA)

Related codes at this level

Codes that share E72.8. If E72.81 is not quite right, the correct code is usually one of these.

Questions about E72.81

Is E72.81 a billable ICD-10-CM code?
Yes. E72.81 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does E72.81 sit in the tabular list?
Endocrine, nutritional and metabolic diseases (E00-E89), in the block Metabolic disorders (E70-E88).
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.