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E72.81

E72.81: Disorders of gamma aminobutyric acid metabolism

Billable / specific codeICD-10-CM

E72.81 is a billable, specific ICD-10-CM code for disorders of gamma aminobutyric acid metabolism. It is valid for submission on a claim.

Check E72.81 with the rest of the claim: free scrubber

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • 4-hydroxybutyric aciduria
  • Disorders of GABA metabolism
  • GABA metabolic defect
  • GABA transaminase deficiency
  • GABA-T deficiency
  • Gamma-hydroxybutyric aciduria
  • SSADHD
  • Succinic semialdehyde dehydrogenase deficiency

Excludes1 inherited from the categories above E72.81

A category’s note binds every code beneath it.

Written on E72: Other disorders of amino-acid metabolism

  • disorders of:
  • aromatic amino-acid metabolism (E70.-)
  • branched-chain amino-acid metabolism (E71.0-E71.2)
  • fatty-acid metabolism (E71.3)
  • purine and pyrimidine metabolism (E79.-)
  • gout (M1A.-, M10.-)

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Alphabetic index entries that lead here

  • SSADHD(succinic semialdehyde dehydrogenase deficiency)
  • Aciduria›4-hydroxybutyric
  • Aciduria›gamma-hydroxybutyric
  • Defect, defective›GABA metabolic(gamma aminobutyric acid)
  • Deficiency, deficient›GABA transaminase(gamma aminobutyric acid)
  • Deficiency, deficient›GABA-T(gamma aminobutyric acid transaminase)
  • Deficiency, deficient›succinic semialdehyde dehydrogenase
  • Disorder›gamma aminobutyric acid metabolism(GABA)

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under E72.8

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.