MCMedicalCodingSoftware
D89.81

D89.81: Graft-versus-host disease

Non-billable headerICD-10-CM

D89.81 is a non-billable header ICD-10-CM code for graft-versus-host disease. It cannot be billed on its own: choose one of the more specific child codes below.

Code first

The underlying condition must be sequenced before this code.

  • underlying cause, such as:
  • complications of transplanted organs and tissue (T86.-)
  • complications of blood transfusion (T80.89)

Use additional code

Add a secondary code to capture the detail described below.

  • code to identify associated manifestations, such as:
  • desquamative dermatitis (L30.8)
  • diarrhea (R19.7)
  • elevated bilirubin (R17)
  • hair loss (L65.9)

Excludes1 inherited from the categories above D89.81

A category’s note binds every code beneath it.

Written on D89: Other disorders involving the immune mechanism, not elsewhere classified

  • hyperglobulinemia NOS (R77.1)
  • monoclonal gammopathy (of undetermined significance) (D47.2)

Excludes2 inherited from the categories above D89.81

Not part of this code, but both may be coded when both are present.

Written on D89: Other disorders involving the immune mechanism, not elsewhere classified

  • transplant failure and rejection (T86.-)

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Code history

Unchanged in every release from FY2024 to FY2027.

Code to one of these instead D89.81

4 child codes. Green means billable.

Other codes under D89.8

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.