D89.3

D89.3: Immune reconstitution syndrome

Billable / specific codeICD-10-CM

D89.3 is a billable, specific ICD-10-CM code for immune reconstitution syndrome. It is valid for submission on a claim.

Check D89.3 with the rest of the claim: free scrubber

Use additional code

Add a secondary code to capture the detail described below.

code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

Immune reconstitution inflammatory syndrome [IRIS]

Excludes1 inherited from the categories above D89.3

A category’s note binds every code beneath it.

Written on D89: Other disorders involving the immune mechanism, not elsewhere classified

hyperglobulinemia NOS (R77.1)
monoclonal gammopathy (of undetermined significance) (D47.2)

Excludes2 inherited from the categories above D89.3

Not part of this code, but both may be coded when both are present.

Written on D89: Other disorders involving the immune mechanism, not elsewhere classified

transplant failure and rejection (T86.-)

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

D89.3 is named in 14 Medicare coverage policies: 14 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

A55717Billing and Coding: Lab: Flow Cytometry
A56464Billing and Coding: Flow Cytometry
A56638Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs)
A56642Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs)