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D89.1

D89.1Cryoglobulinemia

Billable / specific codeICD-10-CM

D89.1 is a billable, specific ICD-10-CM code for cryoglobulinemia. It is valid for submission on a claim.

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Cryoglobulinemic purpura
  • Cryoglobulinemic vasculitis
  • Essential cryoglobulinemia
  • Idiopathic cryoglobulinemia
  • Mixed cryoglobulinemia
  • Primary cryoglobulinemia
  • Secondary cryoglobulinemia

Excludes1 inherited from the categories above D89.1

These are not written on D89.1, but they bind it: a note on a category applies to every code beneath it. Billing D89.1 with anything listed here is a denial.

Written on D89 Other disorders involving the immune mechanism, not elsewhere classified

  • hyperglobulinemia NOS (R77.1)
  • monoclonal gammopathy (of undetermined significance) (D47.2)

Excludes2 inherited from the categories above D89.1

Also inherited, and the opposite of Excludes1: these conditions are not part of D89.1, but a patient can have both, so you may code both.

Written on D89 Other disorders involving the immune mechanism, not elsewhere classified

  • transplant failure and rejection (T86.-)

Other codes that can never be billed with D89.1

These codes carry an Excludes1 note pointing at D89.1. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading D89.1 alone.

  • D69Purpura and other hemorrhagic conditions

Risk adjustment

D89.1 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Medicare coverage

D89.1 is named in 20 Medicare coverage policies 20 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

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How D89.1 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to D89.1.

  • Cryoglobulinemia(essential) (idiopathic) (mixed) (primary) (purpura) (secondary) (vasculitis)
  • Cryoglobulinemiawith lung involvement
  • Purpuracryoglobulinemic
  • Vasculitiscryoglobulinemic
  • Disorderglomerularcryoglobulinemia
  • Disordertubulo-interstitialmixed cryoglobulinemia
  • Glomerulonephritisincryoglobulinemia
  • Pyelonephritisincryoglobulinemia(mixed)
  • Nephritis, nephritictubulo-interstitialdue tocryoglobulinemia

Code history

D89.1 has not changed since FY2024 — no addition, revision or deletion across the three most recent ICD-10-CM releases.

Related codes at this level

Codes that share D89. If D89.1 is not quite right, the correct code is usually one of these.

Questions about D89.1

Is D89.1 a billable ICD-10-CM code?
Yes. D89.1 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does D89.1 sit in the tabular list?
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89), in the block Certain disorders involving the immune mechanism (D80-D89).
What cannot be coded together with D89.1?
D89.1 carries Excludes1 notes, which means the conditions they list can never be coded together with it on the same encounter. Some are written on the categories above D89.1 (D89) and apply to it just the same.
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.