MCMedicalCodingSoftware
D84.1

D84.1: Defects in the complement system

Billable / specific codeICD-10-CM

D84.1 is a billable, specific ICD-10-CM code for defects in the complement system. It is valid for submission on a claim.

Check D84.1 with the rest of the claim: free scrubber

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • C1 esterase inhibitor [C1-INH] deficiency

Other codes that can never be billed with D84.1

Their own Excludes1 notes name this code, so the conflict is not listed above.

  • L50Urticaria
  • D84.81Immunodeficiency due to conditions classified elsewhere

Risk adjustment

D84.1 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:

  • HCC 115 Specified Immunodeficiencies and White Blood Cell Disorders0.565 RAF

Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score. Look up the whole chart to see which of its HCCs the hierarchy would zero.

Medicare coverage

D84.1 is named in 16 Medicare coverage policies: 16 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A55717Billing and Coding: Lab: Flow Cytometry
  • A56464Billing and Coding: Flow Cytometry
  • A56638Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs)
  • A56642Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs)

Alphabetic index entries that lead here

  • Angioedema›hereditary
  • Angioneurotic edema›hereditary
  • Bannister's disease›hereditary
  • Defect, defective›complement system
  • Deficiency, deficient›C1 esterase inhibitor(C1-INH)
  • Quincke's disease or edema›hereditary
  • Edema, edematous›angioneurotic›hereditary
  • Edema, edematous›circumscribed, acute›hereditary
  • Edema, edematous›essential, acute›hereditary
  • Edema, edematous›periodic›hereditary
  • Edema, edematous›Quincke's›hereditary
  • Giant›urticaria›hereditary

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under D84

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.