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D68.4

D68.4Acquired coagulation factor deficiency

Billable / specific codeICD-10-CM

D68.4 is a billable, specific ICD-10-CM code for acquired coagulation factor deficiency. It is valid for submission on a claim.

Excludes1 — never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • vitamin K deficiency of newborn (P53)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Deficiency of coagulation factor due to liver disease
  • Deficiency of coagulation factor due to vitamin K deficiency

Excludes1 inherited from the categories above D68.4

These are not written on D68.4, but they bind it: a note on a category applies to every code beneath it. Billing D68.4 with anything listed here is a denial.

Written on D68 Other coagulation defects

  • abnormal coagulation profile NOS (R79.1)

Excludes2 inherited from the categories above D68.4

Also inherited, and the opposite of Excludes1: these conditions are not part of D68.4, but a patient can have both, so you may code both.

Written on D68 Other coagulation defects

  • coagulation defects complicating abortion or ectopic or molar pregnancy (O00-O07, O08.1)
  • coagulation defects complicating pregnancy, childbirth and the puerperium (O45.0, O46.0, O67.0, O72.3)

Other codes that can never be billed with D68.4

These codes carry an Excludes1 note pointing at D68.4. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading D68.4 alone.

  • E56.1Deficiency of vitamin K
  • R79.1Abnormal coagulation profile

Risk adjustment

D68.4 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Medicare coverage

D68.4 is named in 5 Medicare coverage policies 5 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A55639Billing and Coding: Chemotherapy Agents for Non-Oncologic Conditions
  • A56380Billing and Coding: Rituximab
  • A56416Billing and Coding: Assays for Vitamins and Metabolic Function
  • A57954Billing and Coding: Routine Foot Care

How D68.4 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to D68.4.

  • Hyperprothrombinemia, causing coagulation factor deficiency
  • Fibrinopeniaacquired
  • Hemophiliacalcipriva
  • Hemophilianonfamilial
  • Hypoprothrombinemiaacquired
  • Defect, defectivecoagulationacquired
  • Deficiency, deficientAC globulinacquired
  • Deficiency, deficientcoagulation NOSacquired(any)
  • Deficiency, deficientfibrin-stabilizing factoracquired
  • Deficiency, deficientlabile factoracquired
  • Deficiency, deficientproaccelerinacquired
  • Deficiency, deficientproconvertin factoracquired

Code history

D68.4 has not changed since FY2024 — no addition, revision or deletion across the three most recent ICD-10-CM releases.

Related codes at this level

Codes that share D68. If D68.4 is not quite right, the correct code is usually one of these.

Questions about D68.4

Is D68.4 a billable ICD-10-CM code?
Yes. D68.4 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does D68.4 sit in the tabular list?
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89), in the block Coagulation defects, purpura and other hemorrhagic conditions (D65-D69).
What cannot be coded together with D68.4?
D68.4 carries Excludes1 notes, which means the conditions they list can never be coded together with it on the same encounter. Some are written on the categories above D68.4 (D68) and apply to it just the same.
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.