MCMCB Pro
D59.39

D59.39Other hemolytic-uremic syndrome

Billable / specific codeICD-10-CM

D59.39 is a billable, specific ICD-10-CM code for other hemolytic-uremic syndrome. It is valid for submission on a claim.

Code first

The underlying condition must be sequenced before this code.

  • , if applicable, any associated:
  • COVID-19 (U07.1)
  • complications of kidney transplant (T86.1-)
  • complications of heart transplant (T86.2-)
  • complications of liver transplant (T86.4-)

Use additional code

Add a secondary code to capture the detail described below.

  • code, if applicable, for adverse effect to identify drug (T36-T50 with fifth or sixth character 5)

Code also

Both codes may be needed to describe the encounter fully. Sequencing depends on the reason for the visit.

  • , if applicable, any associated condition, such as:
  • hypertensive emergency (I16.1)
  • malignant neoplasm (C00-C96)
  • systemic lupus erythematosus (M32.-)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Atypical (nongenetic) hemolytic uremic syndrome
  • Secondary hemolytic-uremic syndrome

Risk adjustment

D59.39 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:

  • HCC 109 Acquired Hemolytic, Aplastic, and Sideroblastic Anemias1.144 RAF

Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score.

Medicare coverage

D59.39 is named in 2 Medicare coverage policies 2 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A54548Billing and Coding: Eculizumab, and Biosimilars: EPYSQLI®-eculizumab-aagh, and BKEMV™-eculizumab-aeeb
  • A59186Billing and Coding: Magnesium

How D59.39 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to D59.39.

  • Syndromehemolytic-uremicatypical
  • Syndromehemolytic-uremicsecondary
  • Syndromehemolytic-uremicspecified NEC
  • Syndromehemolytic-uremicatypicalsecondary
  • Syndromehemolytic-uremicatypicalspecified NEC

Related codes at this level

Codes that share D59.3. If D59.39 is not quite right, the correct code is usually one of these.

Questions about D59.39

Is D59.39 a billable ICD-10-CM code?
Yes. D59.39 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does D59.39 sit in the tabular list?
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89), in the block Hemolytic anemias (D55-D59).
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.