MCMedicalCodingSoftware
D59.39

D59.39: Other hemolytic-uremic syndrome

Billable / specific codeICD-10-CM

D59.39 is a billable, specific ICD-10-CM code for other hemolytic-uremic syndrome. It is valid for submission on a claim.

Check D59.39 with the rest of the claim: free scrubber

Code first

The underlying condition must be sequenced before this code.

  • , if applicable, any associated:
  • COVID-19 (U07.1)
  • complications of kidney transplant (T86.1-)
  • complications of heart transplant (T86.2-)
  • complications of liver transplant (T86.4-)

Use additional code

Add a secondary code to capture the detail described below.

  • code, if applicable, for adverse effect to identify drug (T36-T50 with fifth or sixth character 5)

Code also

Both codes may be needed to describe the encounter fully. Sequencing depends on the reason for the visit.

  • , if applicable, any associated condition, such as:
  • hypertensive emergency (I16.1)
  • malignant neoplasm (C00-C96)
  • systemic lupus erythematosus (M32.-)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Atypical (nongenetic) hemolytic uremic syndrome
  • Secondary hemolytic-uremic syndrome

Risk adjustment

D59.39 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:

  • HCC 109 Acquired Hemolytic, Aplastic, and Sideroblastic Anemias1.144 RAF

Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score. Look up the whole chart to see which of its HCCs the hierarchy would zero.

Medicare coverage

D59.39 is named in 2 Medicare coverage policies: 2 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A54548Billing and Coding: Eculizumab, and Biosimilars: EPYSQLI®-eculizumab-aagh, and BKEMV™-eculizumab-aeeb
  • A59186Billing and Coding: Magnesium

Alphabetic index entries that lead here

  • Syndrome›hemolytic-uremic›atypical
  • Syndrome›hemolytic-uremic›secondary
  • Syndrome›hemolytic-uremic›specified NEC
  • Syndrome›hemolytic-uremic›atypical›secondary
  • Syndrome›hemolytic-uremic›atypical›specified NEC

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under D59.3

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.