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D53.1

D53.1: Other megaloblastic anemias, not elsewhere classified

Billable / specific codeICD-10-CM

D53.1 is a billable, specific ICD-10-CM code for other megaloblastic anemias, not elsewhere classified. It is valid for submission on a claim.

Check D53.1 with the rest of the claim: free scrubber

Excludes1: never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • Di Guglielmo's disease (C94.0)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Megaloblastic anemia NOS

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

D53.1 is named in 5 Medicare coverage policies: 5 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A56416Billing and Coding: Assays for Vitamins and Metabolic Function
  • A56464Billing and Coding: Flow Cytometry
  • A56675Billing and Coding: Homocysteine Level, Serum
  • A57188Billing and Coding: Routine Foot Care

Alphabetic index entries that lead here

  • Megalocytic anemia
  • Anemia›achrestic
  • Anemia›dimorphic
  • Anemia›diphasic
  • Anemia›megaloblastic
  • Anemia›megalocytic
  • Anemia›deficiency›combined B12 and folate
  • Anemia›megaloblastic›combined B12 and folate deficiency
  • Anemia›megaloblastic›refractory
  • Anemia›megaloblastic›specified type NEC
  • Anemia›refractory›megaloblastic

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under D53

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.