Is C45 a billable ICD-10-CM code?

No. C45 is a non-billable header code. Code to a higher level of specificity using one of its child codes.

Where does C45 sit in the tabular list?

Neoplasms (C00-D49), in the block Malignant neoplasms of mesothelial and soft tissue (C45-C49).

C45

C45 — Mesothelioma

Non-billable headerICD-10-CM

C45 is a non-billable header ICD-10-CM code for mesothelioma. It cannot be billed on its own: choose one of the more specific child codes below.

Other codes that can never be billed with C45

These codes carry an Excludes1 note pointing at C45. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading C45 alone.

C38Malignant neoplasm of heart, mediastinum and pleura
C48Malignant neoplasm of retroperitoneum and peritoneum

Risk adjustment

C45 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Code to one of these instead C45

5 child codes. Green means billable.

Questions about C45

Is C45 a billable ICD-10-CM code?: No. C45 is a non-billable header code. Code to a higher level of specificity using one of its child codes.
Where does C45 sit in the tabular list?: Neoplasms (C00-D49), in the block Malignant neoplasms of mesothelial and soft tissue (C45-C49).