MCMedicalCodingSoftware
C45

C45: Mesothelioma

Non-billable headerICD-10-CM

C45 is a non-billable header ICD-10-CM code for mesothelioma. It cannot be billed on its own: choose one of the more specific child codes below.

Other codes that can never be billed with C45

Their own Excludes1 notes name this code, so the conflict is not listed above.

  • C38Malignant neoplasm of heart, mediastinum and pleura
  • C48Malignant neoplasm of retroperitoneum and peritoneum

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Code history

Unchanged in every release from FY2024 to FY2027.

Code to one of these instead C45

5 child codes. Green means billable.

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.