Is C22.1 a billable ICD-10-CM code?

Yes. C22.1 is a billable, specific ICD-10-CM code and is valid for submission on a claim.

Where does C22.1 sit in the tabular list?

Neoplasms (C00-D49), in the block Malignant neoplasms of digestive organs (C15-C26).

What cannot be coded together with C22.1?

C22.1 carries an Excludes1 note, which means the conditions it lists can never be coded together with it on the same encounter.

C22.1

C22.1 — Intrahepatic bile duct carcinoma

Billable / specific codeICD-10-CM

C22.1 is a billable, specific ICD-10-CM code for intrahepatic bile duct carcinoma. It is valid for submission on a claim.

Excludes1 — never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

malignant neoplasm of hepatic duct (C24.0)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

Cholangiocarcinoma

Other codes that can never be billed with C22.1

These codes carry an Excludes1 note pointing at C22.1. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading C22.1 alone.

C24Malignant neoplasm of other and unspecified parts of biliary tract

Risk adjustment

C22.1 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:

HCC 20 Lung and Other Severe Cancers1.136 RAF

Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score.

Medicare coverage

C22.1 is named in 73 Medicare coverage policies — 73 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

A52450Billing and Coding: Paclitaxel (e.g., Taxol®/Abraxane ™)
A52479Oral Anticancer Drugs - Policy Article
A52479Oral Anticancer Drugs - Policy Article
A52479Oral Anticancer Drugs - Policy Article

How C22.1 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to C22.1.

Adenocarcinoma›bile duct type
Cancer›bile duct type liver
Cholangiocarcinoma›liver
Cholangiocarcinoma›unspecified site
Cystadenocarcinoma›bile duct
Adenocarcinoma›bile duct type›liver
Adenocarcinoma›bile duct type›unspecified site
Carcinoma›bile duct›liver
Carcinoma›bile duct›unspecified site

Related codes at this level

Codes that share C22. If C22.1 is not quite right, the correct code is usually one of these.

Questions about C22.1

Is C22.1 a billable ICD-10-CM code?: Yes. C22.1 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does C22.1 sit in the tabular list?: Neoplasms (C00-D49), in the block Malignant neoplasms of digestive organs (C15-C26).
What cannot be coded together with C22.1?: C22.1 carries an Excludes1 note, which means the conditions it lists can never be coded together with it on the same encounter.