MCMCB Pro
C22

C22Malignant neoplasm of liver and intrahepatic bile ducts

Non-billable headerICD-10-CM

C22 is a non-billable header ICD-10-CM code for malignant neoplasm of liver and intrahepatic bile ducts. It cannot be billed on its own: choose one of the more specific child codes below.

Excludes1 — never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • malignant neoplasm of biliary tract NOS (C24.9)
  • secondary malignant neoplasm of liver and intrahepatic bile duct (C78.7)

Use additional code

Add a secondary code to capture the detail described below.

Other codes that can never be billed with C22

These codes carry an Excludes1 note pointing at C22. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading C22 alone.

  • C24Malignant neoplasm of other and unspecified parts of biliary tract

Risk adjustment

C22 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Code to one of these instead C22

8 child codes. Green means billable.

Questions about C22

Is C22 a billable ICD-10-CM code?
No. C22 is a non-billable header code. Code to a higher level of specificity using one of its child codes.
Where does C22 sit in the tabular list?
Neoplasms (C00-D49), in the block Malignant neoplasms of digestive organs (C15-C26).
What cannot be coded together with C22?
C22 carries an Excludes1 note, which means the conditions it lists can never be coded together with it on the same encounter.
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.