C9445 — Injection, c-1 esterase inhibitor (recombinant), ruconest, 10 units
C9445 is a HCPCS Level II code for injection, c-1 esterase inhibitor (recombinant), ruconest, 10 units. It belongs to the Outpatient Prospective Payment System section. It was terminated on December 31, 2015 and is not valid on new claims.
This code has been terminated
CMS terminated C9445 on December 31, 2015. It stays in the file as history — a claim you are auditing from before that date may legitimately carry it — but it must not appear on a new claim. The adjacent codes below are the usual place to look for its replacement.
Medicare coverage: Special coverage instructions apply
There are published conditions attached to this code. Check the applicable coverage policy before billing it: the code being valid is not the same as the service being covered.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.
The CMS record for C9445
- Long descriptor
- Injection, c-1 esterase inhibitor (recombinant), ruconest, 10 units
- Short descriptor
- C-1 esterase, ruconest
- Added
- April 1, 2015
- Terminated
- December 31, 2015
- BETOS
- O1E
- Pricing indicator
- 53 — Other
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
When CMS retired it.
Berenson-Eggers Type of Service — CMS's own analytic grouping.
Statute.
Codes adjacent to C9445
HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If C9445 is not quite right, the correct code is very often within a few positions of it.
- C9364Porcine implant, permacol, per square centimeter
- C9399Unclassified drugs or biologicals
- C9407Iodine i-131 iobenguane, diagnostic, 1 millicurieterminated
- C9408Iodine i-131 iobenguane, therapeutic, 1 millicurieterminated
- C9441Injection, ferric carboxymaltose, 1 mgterminated
- C9442Injection, belinostat, 10 mgterminated
- C9443Injection, dalbavancin, 10 mgterminated
- C9444Injection, oritavancin, 10 mgterminated
- C9446Injection, tedizolid phosphate, 1 mgterminated
- C9447Injection, phenylephrine and ketorolac, 4 ml vialterminated
- C9448Netupitant 300 mg and palonosetron 0.5 mg, oralterminated
- C9449Injection, blinatumomab, 1 mcgterminated
- C9450Injection, fluocinolone acetonide intravitreal implant, 0.01 mgterminated
- C9451Injection, peramivir, 1 mgterminated
- C9452Injection, ceftolozane 50 mg and tazobactam 25 mgterminated
- C9453Injection, nivolumab, 1 mgterminated
Questions about C9445
What is HCPCS code C9445?
C9445 is a HCPCS Level II code for injection, c-1 esterase inhibitor (recombinant), ruconest, 10 units. It sits in the Outpatient Prospective Payment System section.
Does Medicare cover C9445?
The CMS HCPCS file marks C9445 as "Special coverage instructions apply". There are published conditions attached to this code. Check the applicable coverage policy before billing it: the code being valid is not the same as the service being covered.
Is C9445 still valid?
No. C9445 was terminated on December 31, 2015 and should not be used on new claims.