MS-DRG 643: ENDOCRINE DISORDERS WITH MCC
MS-DRG 643 is endocrine disorders with mcc, in MDC 10 (a medical DRG), at the with-MCC (major complication or comorbidity) level. Its FY2027 relative weight is 1.6139, so a case here pays more than the average Medicare inpatient stay (weight 1.0), with a geometric mean length of stay of 4.80 days. 199 ICD-10-CM principal diagnoses group into MS-DRGs 643–645 under the CMS definitions manual; the most-searched are listed below.
FY2027 payment factors
- Relative weight
- 1.6139
- Geometric mean LOS
- 4.80
- Arithmetic mean LOS
- 6.10
- Post-acute transfer
- Yes
This DRG is subject to the post-acute care transfer policy: a discharge to a qualifying setting below the mean length of stay is paid per diem rather than in full.
Principal diagnoses that group to MS-DRGs 643–645
From the CMS MS-DRG definitions manual’s principal-diagnosis index: 199 ICD-10-CM codes route here, and the CC/MCC status of the secondary diagnoses decides which of 643–645 the case lands in. The 24 most-searched:
- E29.1Testicular hypofunction
- C73Malignant neoplasm of thyroid gland
- E03.9Hypothyroidism, unspecified
- E04.1Nontoxic single thyroid nodule
- E04.2Nontoxic multinodular goiter
- E21.3Hyperparathyroidism, unspecified
- D35.2Benign neoplasm of pituitary gland
- E23.0Hypopituitarism
- E06.3Autoimmune thyroiditis
- E34.9Endocrine disorder, unspecified
- R94.6Abnormal results of thyroid function studies
- E04.9Nontoxic goiter, unspecified
- E05.00Thyrotoxicosis with diffuse goiter without thyrotoxic crisis or storm
- E05.90Thyrotoxicosis, unspecified without thyrotoxic crisis or storm
- E27.9Disorder of adrenal gland, unspecified
- E03.8Other specified hypothyroidism
- E07.9Disorder of thyroid, unspecified
- E21.0Primary hyperparathyroidism
- E89.0Postprocedural hypothyroidism
- D34Benign neoplasm of thyroid gland
- D44.0Neoplasm of uncertain behavior of thyroid gland
- D49.7Neoplasm of unspecified behavior of endocrine glands and other parts of nervous system
- E02Subclinical iodine-deficiency hypothyroidism
- E22.1Hyperprolactinemia
175 more codes group here. Open any code above for its full hierarchy, or check a whole claim in the free DRG calculator.
The severity splits
Same base DRG, split by whether a secondary diagnosis is a CC or MCC. The last column is the weight change from MS-DRG 643.
| 643 | ENDOCRINE DISORDERS WITH MCC | 1.6139 | |
| 644 | ENDOCRINE DISORDERS WITH CC | 1.0044 | -0.6095 |
| 645 | ENDOCRINE DISORDERS WITHOUT CC/MCC | 0.7459 | -0.8680 |
All FY2027 MS-DRGs · MDC 10