MS-DRG 546: CONNECTIVE TISSUE DISORDERS WITH CC
MS-DRG 546 is connective tissue disorders with cc, in MDC 08 (a medical DRG), at the with-CC (complication or comorbidity) level. Its FY2027 relative weight is 1.1745, so a case here pays more than the average Medicare inpatient stay (weight 1.0), with a geometric mean length of stay of 3.30 days. 562 ICD-10-CM principal diagnoses group into MS-DRGs 545–547 under the CMS definitions manual; the most-searched are listed below.
FY2027 payment factors
- Relative weight
- 1.1745
- Geometric mean LOS
- 3.30
- Arithmetic mean LOS
- 4.30
- Post-acute transfer
- Yes
This DRG is subject to the post-acute care transfer policy: a discharge to a qualifying setting below the mean length of stay is paid per diem rather than in full.
Principal diagnoses that group to MS-DRGs 545–547
From the CMS MS-DRG definitions manual’s principal-diagnosis index: 562 ICD-10-CM codes route here, and the CC/MCC status of the secondary diagnoses decides which of 545–547 the case lands in. The 24 most-searched:
- M32.9Systemic lupus erythematosus, unspecified
- M05.79Rheumatoid arthritis with rheumatoid factor of multiple sites without organ or systems involvement
- M06.9Rheumatoid arthritis, unspecified
- L40.50Arthropathic psoriasis, unspecified
- E85.4Organ-limited amyloidosis
- M35.9Systemic involvement of connective tissue, unspecified
- M05.9Rheumatoid arthritis with rheumatoid factor, unspecified
- M06.00Rheumatoid arthritis without rheumatoid factor, unspecified site
- M06.09Rheumatoid arthritis without rheumatoid factor, multiple sites
- M35.00Sjogren syndrome, unspecified
- M45.9Ankylosing spondylitis of unspecified sites in spine
- I77.6Arteritis, unspecified
- L40.59Other psoriatic arthropathy
- M32.10Systemic lupus erythematosus, organ or system involvement unspecified
- M33.13Other dermatomyositis without myopathy
- M34.9Systemic sclerosis, unspecified
- M35.3Polymyalgia rheumatica
- E85.81Light chain (AL) amyloidosis
- E85.82Wild-type transthyretin-related (ATTR) amyloidosis
- E85.9Amyloidosis, unspecified
- I73.00Raynaud's syndrome without gangrene
- M31.6Other giant cell arteritis
- M33.20Polymyositis, organ involvement unspecified
- M35.1Other overlap syndromes
538 more codes group here. Open any code above for its full hierarchy, or check a whole claim in the free DRG calculator.
The severity splits
Same base DRG, split by whether a secondary diagnosis is a CC or MCC. The last column is the weight change from MS-DRG 546.
| 545 | CONNECTIVE TISSUE DISORDERS WITH MCC | 2.3892 | +1.2147 |
| 546 | CONNECTIVE TISSUE DISORDERS WITH CC | 1.1745 | |
| 547 | CONNECTIVE TISSUE DISORDERS WITHOUT CC/MCC | 0.7526 | -0.4219 |
All FY2027 MS-DRGs · MDC 08